Evidence map›Paper›PMID 36719428›Full record

Observational studyEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2023

Clinical practice selectively follows acute appendicitis guidelines.

Gary Alan Bass, Shahin Mohseni, Éanna J Ryan, Maximilian Peter Forssten, Matti Tolonen, Yang Cao, Lewis J Kaplan, ESTES SnapAppy Group

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Practice patterns and clinical outcomes in acute appendicitis differ in the elderly patient.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Observational
  11. Article
  12. European society for trauma and emergency surgery member-identified research priorities in emergency surgery: a roadmap for future clinical research opportunities.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Review
  13. Article
  14. Article
  15. Review
  16. Focus on identifying and closing knowledge gaps in acute appendicitis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 5 countries.

Gary Alan BassDivision of Traumatology, Surgical Critical Care & Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA. gary.bass@pennmedicine.upenn.edu.
Shahin MohseniDivision of Trauma & Emergency Surgery, Orebro University Hospital and School of Medical Sciences, Orebro University, Örebro, Sweden. mohsenishahin@yahoo.com.ORCID http://orcid.org/0000-0001-7097-487X
Éanna J RyanTallaght University Hospital, Dublin, Ireland.
Maximilian Peter ForsstenDivision of Trauma & Emergency Surgery, Orebro University Hospital and School of Medical Sciences, Orebro University, Örebro, Sweden.
Matti TolonenHelsinki University Hospital HUS Meilahden Tornisairaala, Helsinki, Finland.
Yang CaoDepartment of Clinical Epidemiology and Biostatistics, School of Medical Sciences, Orebro University, Orebro, Sweden.
Lewis J KaplanDivision of Traumatology, Surgical Critical Care & Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA.
ESTES SnapAppy Group
Örebro University · SETallaght University Hospital · IEHelsinki University Hospital · FIUniversity of Pennsylvania · USVeterans Health Administration · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcute appendicitis is a common surgical emergency, and the standard approach to diagnosis and management has been codified in several practice guidelines. Adherence to these guidelines provides insight into independent surgical practice patterns and institutional resource constraints as impediments to best practice. We explored data from the recent ESTES SnapAppy observational cohort study to determine guideline compliance in contemporary practice to identify opportunities to close evidence-to-practice gaps.

methodsWe undertook a preplanned analysis of the ESTES SnapAppy observational cohort study, identifying, at a patient level, congruence with, or deviation from WSES Jerusalem guidelines for the diagnosis and management of acute appendicitis and the Surviving Sepsis Campaign in our cohort. Compliance was then correlated with the incidence of postoperative complications.

resultsFour thousand six hundred and thirteen (4613) consecutive adult and adolescent patients with acute appendicitis were followed from date of admission (November 1, 2020, and May 28, 2021) for 90 days. Patient-level compliance with guideline elements allowed patients to be grouped into those with full compliance (all 5 elements: 13%), partial compliance (1-4 elements: 87%) or noncompliance (0 elements: 0.2%). We identified an excess postoperative complication rate in patients who received noncompliant and partially compliant care, compared with those who received fully guideline-compliant care (36% and 16%, versus 7.3%, p < 0.001).

conclusionsThe observed diagnostic and treatment practices of the participating institutions displayed variability in compliance with key recommendations from existing guidelines. In general, practice was congruent with recommendations for preoperative antibiotic surgical site infection prophylaxis administration, time to surgery, and operative approach. However, there remains opportunities for improvement in the choice of diagnostic imaging modality, postoperative antibiotic stewardship to timely discontinue prophylactic antibiotics, and the implementation of ambulatory treatment pathways for uncomplicated appendicitis in the healthy young adult.

Indexed as

AppendicitisAdolescentAnti-Bacterial AgentsAntibiotic ProphylaxisAppendectomyHumansSurgical Wound InfectionYoung AdultAnti-Bacterial AgentsAcute appendicitisAppendectomyGuidelinesObservational cohort

Identifiers

PMID36719428
PMCPMC9888346
OpenAlexW4318669337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.