Evidence map›Paper›PMID 36719346›Full record

ArticleCancer medicine2023

Survival disadvantage of male children with retinoblastoma in the United States: Surveillance Epidemiology and End Results (2000-2017) Evidence.

Laurens Holmes, Emily Pollack, Betyna N Berice, Daniel R Halloran, Kadedrah Parson, Nastocia T Badfford, Lavisha Paleaz, Jacqueline A Benson

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Laurens HolmesNemours/Alfred I. DuPont Hospital for Children, Office of Health Equity & Inclusion, Health Disparities Science Research, Wilmington, DE, USA.
Emily PollackNemours/Alfred I. DuPont Hospital for Children, Office of Health Equity & Inclusion, Health Disparities Science Research, Wilmington, DE, USA.
Betyna N BericeNemours/Alfred I. DuPont Hospital for Children, Office of Health Equity & Inclusion, Health Disparities Science Research, Wilmington, DE, USA.ORCID 0000-0003-0544-149X
Daniel R HalloranNemours/Alfred I. DuPont Hospital for Children, Office of Health Equity & Inclusion, Health Disparities Science Research, Wilmington, DE, USA.
Kadedrah ParsonNemours/Alfred I. DuPont Hospital for Children, Office of Health Equity & Inclusion, Health Disparities Science Research, Wilmington, DE, USA.
Nastocia T BadffordNemours/Alfred I. DuPont Hospital for Children, Office of Health Equity & Inclusion, Health Disparities Science Research, Wilmington, DE, USA.
Lavisha PaleazNemours/Alfred I. DuPont Hospital for Children, Office of Health Equity & Inclusion, Health Disparities Science Research, Wilmington, DE, USA.
Jacqueline A BensonNemours/Alfred I. DuPont Hospital for Children, Office of Health Equity & Inclusion, Health Disparities Science Research, Wilmington, DE, USA.ORCID 0000-0002-8902-7589
DuPont (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRetinoblastoma is a rare malignancy involving the retina, although, more common among children, with genetic inheritance explaining the incidence as well as acquired forms. The incidence varies among race and sex as well as mortality and survival. The current study aimed to assess retinoblastoma cumulative incidence (CMI), mortality, and survival by sex.

methodsA retrospective cohort design was used to assess the CMI, mortality, and survival in this pediatric malignancy based on the Surveillance Epidemiology and End Results (SEER) data 2000-2017. The binomial regression model was used to examine sex differentials in mortality, as well as other study variables, while Cox proportional hazard model was used for the survival variability by sex.

resultsThe CMI during this period was higher among males relative to females (males n = 249, 56.7%; females n = 190, 43.3%, χ

conclusionIn a representative sample of pediatric retinoblastoma, there was a sex differential in survival with excess risk of dying identified among males relative to females, which may be explained in part by male X-linkage.

Indexed as

Retinal NeoplasmsRetinoblastomaChildFemaleHumansIncidenceMaleProportional Hazards ModelsRetrospective StudiesSEER ProgramUnited Statesepidemiology and preventionepigeneticshealth disparity pediatric cancerretinoblastomaSEER

Identifiers

PMID36719346
PMCPMC9972039
OpenAlexW4318671460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.