ArticleeLife2023
Olfactory receptor neurons generate multiple response motifs, increasing coding space dimensionality.
Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Anatomical Investigation Reveals a Second Olfactory System in Locusts.The Journal of comparative neurology · 2026Article
- Data-Constrained Recurrent Network Neural Model Uncovers the Circuit Mechanism of Olfactory OFF Responses.bioRxiv : the preprint server for biology · 2026Article
- Article
- Stimulus duration encoding occurs early in the moth olfactory pathway.Communications biology · 2024Article
- Article
- Olfactory system structure and function in newly hatched and adult locusts.Scientific reports · 2024Article
- Olfactory receptor neurons generate multiple response motifs, increasing coding space dimensionality.eLife · 2023Article
- Innate attraction and aversion to odors in locusts.PloS one · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
Odorants binding to olfactory receptor neurons (ORNs) trigger bursts of action potentials, providing the brain with its only experience of the olfactory environment. Our recordings made in vivo from locust ORNs showed that odor-elicited firing patterns comprise four distinct response motifs, each defined by a reliable temporal profile. Different odorants could elicit different response motifs from a given ORN, a property we term motif switching. Further, each motif undergoes its own form of sensory adaptation when activated by repeated plume-like odor pulses. A computational model constrained by our recordings revealed that organizing responses into multiple motifs provides substantial benefits for classifying odors and processing complex odor plumes: each motif contributes uniquely to encode the plume's composition and structure. Multiple motifs and motif switching further improve odor classification by expanding coding dimensionality. Our model demonstrated that these response features could provide benefits for olfactory navigation, including determining the distance to an odor source.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.