Evidence map›Paper›PMID 36718862›Full record

ArticleJournal of the American Heart Association2023

Health Status Outcomes in Older Adults Undergoing Chronic Total Occlusion Percutaneous Coronary Intervention.

Dan D Nguyen, Kensey L Gosch, Rayan El-Zein, Paul S Chan, William L Lombardi, Dimitri Karmpaliotis, John A Spertus, R Michael Wyman, William J Nicholson, Jeffrey W Moses and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. A multidimensional item response theory analysis of the Seattle Angina Questionnaire: measurement precision, differential item functioning, and potential for item reduction.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  2. Characterizing heterogeneity in health-related quality of life trajectories in coronary artery disease: a longitudinal latent Markov analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Dan D NguyenSaint Luke's Mid America Heart Institute Kansas City MO.ORCID 0000-0001-7025-4442
Kensey L GoschSaint Luke's Mid America Heart Institute Kansas City MO.ORCID 0000-0003-2934-6913
Rayan El-ZeinSaint Luke's Mid America Heart Institute Kansas City MO.
Paul S ChanSaint Luke's Mid America Heart Institute Kansas City MO.ORCID 0000-0002-5185-3367
William L LombardiUniversity of Washington Medical Center Seattle WA.
Dimitri KarmpaliotisMorristown Medical Center Morristown NJ.
John A SpertusSaint Luke's Mid America Heart Institute Kansas City MO.ORCID 0000-0002-2839-2611
R Michael WymanTorrance Memorial Medical Center Torrance CA.ORCID 0000-0002-4133-3042
William J NicholsonEmory University Atlanta GA.
Jeffrey W MosesColumbia University Medical Center New York NY.ORCID 0000-0002-8842-7919
J Aaron GranthamSaint Luke's Mid America Heart Institute Kansas City MO.
Adam C SalisburySaint Luke's Mid America Heart Institute Kansas City MO.ORCID 0000-0003-1161-6356
OPEN‐CTO Study Group *
Saint Luke's Hospital · USColumbia University Irving Medical Center · USEmory University · USMorristown Medical Center · USTorrance Memorial Medical Center · USUniversity of Washington Medical Center · US

Funding

CARDIOVASCULAR OUTCOMES RESEARCH TRAINING PROGRAMT32HL110837 · NHLBI · UNIVERSITY OF MISSOURI KANSAS CITY · PI JOHN A SPERTUS · 2012 to 2026
$5.0M
Reducing Ethnic-racial Disparities in Cardiac Arrest Survival Outcomes (RED-CASO)R01HL160734 · NHLBI · SAINT LUKE'S HOSPITAL · PI CHAN, PAUL SHEUNG-YAN, GIROTRA, SAKET · 2022 to 2025
$2.6M
NHLBI NIH HHS R01 HL160734NHLBI NIH HHS T32 HL110837
6 · The paper itself

Abstract

Background Although chronic total occlusions (CTOs) are common in older adults, they are less likely to be offered CTO percutaneous coronary intervention for angina relief than younger adults. The health status impact of CTO percutaneous coronary intervention in adults aged ≥75 years has not been studied. We sought to compare technical success rates and angina-related health status outcomes at 12 months between adults aged ≥75 and <75 years in the OPEN-CTO (Outcomes, Patient Health Status, and Efficiency in Chronic Total Occlusion) registry. Methods and Results Angina-related health status was assessed with the Seattle Angina Questionnaire (score range 0-100, higher scores denote less angina). Technical success rates were compared using hierarchical modified Poisson regression, and 12-month health status was compared using hierarchical multivariable linear regression between adults aged ≥75 and <75 years. Among 1000 participants, 19.8% were ≥75 years with a mean age of 79.5±4.1 years. Age ≥75 years was associated with a lower likelihood of technical success (adjusted risk ratio=0.92 [95% CI, 0.86-0.99;

Indexed as

Coronary OcclusionPercutaneous Coronary InterventionAgedAged, 80 and overAngina PectorisChronic DiseaseCoronary AngiographyHealth StatusHumansRegistriesRisk FactorsTreatment Outcomechronic total occlusionhealth statusolder adultspercutaneous coronary intervention

Identifiers

PMID36718862
PMCPMC9973646
OpenAlexW4318617180

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.