Evidence map›Paper›PMID 36718466›Full record

ArticleChemistrySelect2022

Synthesis and In Silico Investigation of Isatin-Based Schiff Bases as Potential Inhibitors for Promising Targets against SARS-CoV-2.

Zohreh Esam, Malihe Akhavan, Maryam Lotfi, Ahmadreza Bekhradnia

Open access · greenAbstract read
In one paragraph

Article in ChemistrySelect, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Zohreh EsamPharmaceutical Sciences Research Center Department of Medicinal Chemistry Faculty of Pharmacy Mazandaran University of Medical Sciences Sari Iran.
Malihe AkhavanPharmaceutical Sciences Research Center Department of Medicinal Chemistry Faculty of Pharmacy Mazandaran University of Medical Sciences Sari Iran.
Maryam LotfiThe Multiscale Modeling Lab, ITQB NOVA Av. da Republica 2780-157 Oeiras Portugal.
Ahmadreza BekhradniaPharmaceutical Sciences Research Center Department of Medicinal Chemistry Faculty of Pharmacy Mazandaran University of Medical Sciences Sari Iran.ORCID 0000-0002-7155-4532
Mazandaran University of Medical Sciences · IRInstituto Português Da Qualidade · PTMontana State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the significant development in vaccines and therapeutics cocktails, there is no specific treatment available for coronavirus disease 2019 (COVID-19), caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Targeting the main protease (M

Indexed as

COVID-19Main proteaseMolecular dynamics, RdRpSARS-CoV-2SpikeSynthesis design, TMPRSS2

Identifiers

PMID36718466
PMCPMC9878032
OpenAlexW4312106441

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.