Evidence map›Paper›PMID 36718311›Full record

ArticleReports of biochemistry & molecular biology2022

Raghda Makia, Khulood Al-Sammarrae, Mohammad Al-Halbosiy, Mohammed Al-Mashhadani

Open access · goldAbstract read
In one paragraph

Article in Reports of biochemistry & molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Effect of Active Compounds of Eruca Sativa Plant Extract onReports of biochemistry & molecular biology · 2024
    Article
  4. Article
  5. Anti-Cancer Effect ofReports of biochemistry & molecular biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Raghda MakiaBiotechnology College, Al-Nahrain University Baghdad, Iraq.
Khulood Al-SammarraeDepartment of Forensic Techniques, Al-Farahidi University, Baghdad, Iraq.
Mohammad Al-HalbosiyBiotechnology Research Center, Al-Nahrain University, Baghdad, Iraq.
Mohammed Al-MashhadaniDepartment of Chemistry, College of Science, Al-Nahrain University, Baghdad, Iraq.
Nahrain University · IQIraqi University · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Normally happening substances like flavonoids are regarded as active candidates for the treatment and prevention of cancer The purpose of this study was to see how Iraqi Methods: Plant powder was extracted by reflex apparatus, then thin-layer chromatography (TLC) was used to determine total flavonoids. Cytotoxicity assay (MTT) was used to determine the cytotoxic activity of the prepared plant against human breast cancer (MCF-7), cells human cervix cancer (HELA), human colon cancer (Caco-2) and human lung fibroblast normal cell line (WISH). Results: The flavonoids Rutin, Quercetin, Kaempferol, and luteolin were detected using the Thin Layer Chromatography (TLC) technique. In contrast to the negative control, the extract inhibited cell growth to a highest of 82.158% for MCF-7 and 61.360% for Caco-2 at the concentration (100 µg/ml), and (54.880%) for Hela cell line at the concentration (100 µg/ml). In addition, the concentration (6.25 µg/ml) of total flavonoid extract produced a decrease in the growth of the normal WISH cell line to reach (1.094%). Conclusion:

Indexed as

Caco2Equisetum arvense LHelaMCF-7Total flavonoidWISH

Identifiers

PMID36718311
PMCPMC9883023
OpenAlexW4316627457

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.