ArticleMedical devices (Auckland, N.Z.)2023
Assessment of a Non-Invasive Brain Pulse Monitor to Measure Intra-Cranial Pressure Following Acute Brain Injury.
Article in Medical devices (Auckland, N.Z.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Intracranial Pressure Estimation Using B4C Device: A Systematic Review on the Validation Studies.Neurocritical care · 2026Review
- Development and optical characterization of a multilayered head phantom for optical brain monitoring.Journal of biomedical optics · 2026Article
- Performance of Intracranial Pressure Waveform Morphological Features as Biomarkers of Intracranial Hypertension.Critical care explorations · 2026Article
- Machine learning-driven microwave system for noninvasive monitoring of intracranial pressure.Biomedical engineering online · 2025Article
- In Vitro Evaluation of Confounders in Brain Optical Monitoring: A Review.Sensors (Basel, Switzerland) · 2025Review
- A Novel Approach to Non-Invasive Intracranial Pressure Wave Monitoring: A Pilot Healthy Brain Study.Sensors (Basel, Switzerland) · 2025Article
- Prospective comparative clinical trials of novel non-invasive intracranial pressure pulse wave monitoring technologies: preliminary clinical data.Interface focus · 2024Article
- A Point-of-Care Noninvasive Technique for Surrogate ICP Waveforms Application in Neurocritical Care.Neurocritical care · 2024Article
- The Development of Non-Invasive Optical Brain Pulse Monitoring: A Review.Medical devices (Auckland, N.Z.) · 2024Review
- Cerebrovascular Responses in a Patient with Lundberg B Waves Following Subarachnoid Haemorrhage Assessed with a Novel Non-Invasive Brain Pulse Monitor: A Case Report.Medical devices (Auckland, N.Z.) · 2024Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Intracranial pressure (ICP) monitoring requires placing a hole in the skull through which an invasive pressure monitor is inserted into the brain. This approach has risks for the patient and is expensive. We have developed a non-invasive brain pulse monitor that uses red light to detect a photoplethysmographic (PPG) signal arising from the blood vessels on the brain's cortical surface. The brain PPG and the invasive ICP waveform share morphological features which may allow measurement of the intracranial pressure. Methods: We enrolled critically ill patients with an acute brain injury with invasive ICP monitoring to assess the new monitor. A total of 24 simultaneous invasive ICP and brain pulse monitor PPG measurements were undertaken in 12 patients over a range of ICP levels. Results: The waveform morphologies were similar for the invasive ICP and brain pulse monitor PPG approach. Both methods demonstrated a progressive increase in the amplitude of P2 relative to P1 with increasing ICP levels. An automated algorithm was developed to assess the PPG morphological features in relation to the ICP level. A correlation was demonstrated between the brain pulse waveform morphology and ICP levels, R Conclusion: The brain pulse monitor's PPG waveform demonstrated morphological features were similar to the invasive ICP waveform over a range of ICP levels, these features may provide a method to measure ICP levels. Trial Registration: ACTRN12620000828921.
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