Evidence map›Paper›PMID 36717957›Full record

ArticleParasites & vectors2023

Localization of secreted ferritin (FER2) in the embryos of the tick Haemaphysalis longicornis.

Emmanuel Pacia Hernandez, Kei Shimazaki, Hiroko Niihara, Rika Umemiya-Shirafuji, Kozo Fujisaki, Tetsuya Tanaka

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Emmanuel Pacia Hernandez *Department of Veterinary Paraclinical Sciences, College of Veterinary Medicine, University of the Philippines at Los Baños College, 3004, Laguna, Philippines.
Kei Shimazaki *Laboratory of Infectious Diseases, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima, 890-0056, Japan.
Hiroko NiiharaLaboratory of Infectious Diseases, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima, 890-0056, Japan.
Rika Umemiya-ShirafujiNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, 080-8555, Japan.
Kozo FujisakiNational Agricultural and Food Research Organization, 3-1-5 Kannondai, Tsukuba, Ibaraki, 305-0856, Japan.
Tetsuya TanakaLaboratory of Infectious Diseases, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima, 890-0056, Japan. k6199431@kadai.jp.
Kagoshima University · JPNational Agriculture and Food Research Organization · JPObihiro University of Agriculture and Veterinary Medicine · JPUniversity of the Philippines Los Baños · PH

Funding

Japan Society for the Promotion of Science JP20KK0154National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine 2020 joint-2 and 2021 joint-6
6 · The paper itself

Abstract

Despite the absence of a blood meal, embryogenesis involves many processes that require nutrients and other essential elements, including iron. Due to the lack of an external source of these nutrients, these requirements are acquired maternally. Because of the toxic nature of iron, they are transferred through iron transport molecules such as secreted ferritin (FER2). Here we tried to follow the trail of the FER2 through indirect immunofluorescence, and we observed an apparent shift of FER2 from the germ layer at the early part of development to the appendages during the late stage of embryogenesis. FER2 is also found in the middle part of the legs of the embryo. The apparent movement not only sheds light on iron processing events during embryogenesis but also indirectly guides organogenesis in the tick.

Indexed as

IxodidaeTicksAnimalsFerritinsIronFerritinsIron

Identifiers

PMID36717957
PMCPMC9885654
OpenAlexW4318478127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.