ArticleJournal of orthopaedic surgery and research2023
Mechanical performance of porous biomimetic intervertebral body fusion devices: an in vitro biomechanical study.
Article in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Innovative animal models for surgical interventions and implant biocompatibility: a translational perspective.Annals of medicine and surgery (2012) · 2025Review
- Analysis of the anti-subsidence mechanical properties of novel 3D-printed titanium cages compared to conventional titanium cages.Journal of orthopaedic surgery and research · 2025Article
- Finite element analysis of short-segment fixation combined with expandable polyetheretherketone vertebral body replacement in osteoporotic vertebrae.BMC musculoskeletal disorders · 2025Article
- Comparison of residual stress distribution between root-analogue implant and threaded cylindrical implant.BMC oral health · 2025Article
- A Finite Element Study of Simulated Fusion in an L4-L5 Model: Influence of the Combination of Materials in the Screw-and-Rod Fixation System on Reproducing Natural Bone Behavior.Biomimetics (Basel, Switzerland) · 2025Article
- Overloaded Vertebral Body Following Consecutive Three-Level Hybrid Surgery Comparing with Anterior Cervical Discectomy and Fusion.Orthopaedic surgery · 2024Article
- Experimental Analysis of Stress Shielding Effects in Screw Spacers Placed in Porcine Spinal Tissue.Journal of functional biomaterials · 2024Article
- Article
- Implant Surface Technologies to Promote Spinal Fusion: A Narrative Review.International journal of spine surgery · 2023Article
- Overloaded vertebral body: a unique radiographic phenomenon following multilevel anterior cervical discectomy and fusion.Journal of orthopaedic surgery and research · 2023Article
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5 authors.
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Abstract
backgroundDegenerative disc disease is one of the most common ailments severely affecting the quality of life in elderly population. Cervical intervertebral body fusion devices are utilized to provide stability after surgical intervention for cervical pathology. In this study, we design a biomimetic porous spinal cage, and perform mechanical simulations to study its performances following American Society for Testing and Materials International (ASTM) standards before manufacturing to improve design process and decrease cost and consumption of material.
methodsThe biomimetic porous Ti-6Al-4 V interbody fusion devices were manufactured by selective laser melting (laser powder bed fusion: LPBF in ISO/ASTM 52900 standard) and subsequently post-processed by using hot isostatic pressing (HIP). Chemical composition, microstructure and the surface morphology were studied. Finite element analysis and in vitro biomechanical test were performed.
findingsThe post heat treatment can optimize its mechanical properties, as the stiffness of the cage decreases to reduce the stress shielding effect between two instrumented bodies. After the HIP treatment, the ductility and the fatigue performance are substantially improved. The use of HIP post-processing can be a necessity to improve the physical properties of customized additive manufacturing processed implants.
interpretationIn conclusion, we have successfully designed a biomimetic porous intervertebral device. HIP post-treatment can improve the bulk material properties, optimize the device with reduced stiffness, decreased stress shielding effect, while still provide appropriate space for bone growth. CLINICAL SIGNIFICANCE: The biomechanical performance of 3-D printed biomimetic porous intervertebral device can be optimized. The ductility and the fatigue performance were substantially improved, the simultaneously decreased stiffness reduces the stress shielding effect between two instrumented bodies; while the biomimetic porous structures provide appropriate space for bone growth, which is important in the patients with osteoporosis.
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