Evidence map›Paper›PMID 36717621›Full record

ArticleScientific reports2023

Epidemiology of GII.4 and GII.2 norovirus outbreaks in closed and semi-closed institutions in 2017 and 2018.

Thais Cornejo-Sánchez, Núria Soldevila, Lorena Coronas, Miquel Alsedà, Pere Godoy, Efrén Razquín, Sara Sabaté, Susana Guix, Virginia Rodríguez Garrido, Rosa Bartolomé and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Thais Cornejo-SánchezLaboratori de Microbiologia, Hospital Universitari Vall d'Hebrón, Barcelona, Spain.
Núria SoldevilaCIBER Epidemiología y Salut Pública (CIBERSP), Madrid, Spain. nsoldevila@ub.edu.
Lorena CoronasDepartament de Medicina, Universitat de Barcelona, Barcelona, Spain.
Miquel AlsedàAgència de Salut Pública de Catalunya, Barcelona, Spain.
Pere GodoyCIBER Epidemiología y Salut Pública (CIBERSP), Madrid, Spain.
Efrén RazquínAgència de Salut Pública de Barcelona (ASPB), Barcelona, Spain.
Sara SabatéAgència de Salut Pública de Barcelona (ASPB), Barcelona, Spain.
Susana GuixDepartament de Genètica Microbiologia i Estadística, Grup de Virus Entèrics, Universitat de Barcelona, Barcelona, Spain.
Virginia Rodríguez GarridoLaboratori de Microbiologia, Hospital Universitari Vall d'Hebrón, Barcelona, Spain.
Rosa BartoloméLaboratori de Microbiologia, Hospital Universitari Vall d'Hebrón, Barcelona, Spain.
Angela DomínguezCIBER Epidemiología y Salut Pública (CIBERSP), Madrid, Spain.
Working Group for the Study of Outbreaks of Acute Gastroenteritis in Catalonia
Agència de Salut Pública de Catalunya · ESCentro de Investigación Biomédica en Red · ESVall d'Hebron Hospital Universitari · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Norovirus infections are a leading cause of acute gastroenteritis outbreaks worldwide, with genotypes GII.2 and GII.4 being the most prevalent. The aim of this study was to compare the characteristics of GII.2 and GII.4 norovirus outbreaks reported in Catalonia in closed or semi-closed institutions in 2017 and 2018. The epidemiological and clinical characteristics of GII.2 and GII.4 outbreaks were compared using the chi-square test or Fisher's exact test for categorical variables and the Mann-Whitney U test for continuous variables. Odds ratios and their 95% confidence intervals were estimated. 61 outbreaks were reported: GII.4 was the causative agent in 12 outbreaks (30%) and GII.2 in 9 outbreaks (22.5%). GII.2 outbreaks were detected more frequently in schools or summer camps (66.7%) and GII.4 outbreaks in nursing homes (91.7%) (p = 0.01). Ninety-three people were affected in GII.2 outbreaks and 94 in GII.4 outbreaks. The median age was 15 years (range: 1-95 years) in GII.2 outbreaks and 86 years (range: 0-100 years) in GII.4 outbreaks (p < 0.001). Nausea, abdominal pain, and headache were observed more frequently in persons affected by GII.2 outbreaks (p < 0.05). Symptomatic cases presented a higher viral load suggestive of greater transmission capacity, although asymptomatic patients presented relevant loads indicative of transmission capacity.

Indexed as

Caliciviridae InfectionsGastroenteritisNorovirusAdolescentDisease OutbreaksGenotypeHumansMolecular EpidemiologyPhylogeny

Identifiers

PMID36717621
PMCPMC9886968
OpenAlexW4318478189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.