Evidence map›Paper›PMID 36717607›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2023

Association between pharmacologic treatment and hospital utilization at birth among neonatal opioid withdrawal syndrome mother-infant dyads.

Phillip D Hahn, Patrice Melvin, Dionne A Graham, Al Ozonoff, Carly E Milliren

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Prenatal Opioid Exposure and Neonatal Opioid Withdrawal Syndrome.Advances in experimental medicine and biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Phillip D HahnProgram for Patient Safety and Quality, Boston Children's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-7666-7632
Patrice MelvinOffice of Health Equity and Inclusion, Boston Children's Hospital, Boston, MA, USA.
Dionne A GrahamProgram for Patient Safety and Quality, Boston Children's Hospital, Boston, MA, USA.
Al OzonoffDepartment of Pediatrics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-4233-5899
Carly E MillirenInstitutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, MA, USA. carly.milliren@childrens.harvard.edu.ORCID http://orcid.org/0000-0001-6280-8417

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe linked mother-baby dyads to explore associations between maternal medication-assisted therapy (MAT) and infants' pharmacologic treatment on birth hospital utilization for infants with NOWS.

methodsWe extracted singleton infant and maternal delivery discharges from PHIS hospitals with large volumes of deliveries for 2016-2019. We matched newborns with NOWS to maternal delivery discharges by hospital, day of birth, mode of delivery, and ZIP code. We examined the association between maternal MAT, infants' pharmacologic treatment, and hospital utilization at birth.

resultsWe included N = 146 mother-baby dyads from six hospitals (74% match rate). Among matched dyads, 51% received maternal MAT, 60% pharmacotherapy (37% both). Infants treated non-pharmacologically and born to mothers receiving MAT had the shortest stays vs. infants without pharmacotherapy or MAT (RR = 0.29; 95% CI: 0.25-0.35).

conclusionsThese findings underscore the importance of adequate perinatal treatment for opioid use disorder to improve outcomes for mothers and infants with opioid exposure.

Indexed as

Neonatal Abstinence SyndromeOpioid-Related DisordersAnalgesics, OpioidFemaleHospitalsHumansInfantInfant, NewbornMothersPregnancyAnalgesics, Opioid

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.