Evidence map›Paper›PMID 36717434›Full record

ArticleSocial psychiatry and psychiatric epidemiology2023

Five-year illness trajectories across racial groups in the UK following a first episode psychosis.

Siân Lowri Griffiths, Tumelo Bogatsu, Mia Longhi, Emily Butler, Beel Alexander, Mrunal Bandawar, Linda Everard, Peter B Jones, David Fowler, Joanne Hodgekins and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Investigating inequalities in patient outcomes for first-episode psychosis.The British journal of psychiatry : the journal of mental science · 2024
    Observational
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 1 country.

Siân Lowri GriffithsInstitute for Mental Health, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. s.l.griffiths@bham.ac.uk.ORCID http://orcid.org/0000-0003-0031-7174
Tumelo BogatsuInstitute for Mental Health, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Mia LonghiInstitute for Mental Health, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Emily ButlerInstitute for Mental Health, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Beel AlexanderInstitute for Mental Health, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Mrunal BandawarInstitute for Mental Health, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Linda EverardBirmingham and Solihull Mental Health Foundation Trust, Birmingham, UK.
Peter B JonesDepartment of Psychiatry, University of Cambridge and CAMEO, Cambridge and Peterborough NHS Foundation Trust, Fulbourn, UK.
David FowlerDepartment of Psychology, University of Sussex, Brighton, UK.
Joanne HodgekinsNorwich Medical School, University of East Anglia, Norwich, UK.
Tim AmosAcademic Unit of Psychiatry, University of Bristol, Bristol, UK.
Nick FreemantleInstitute of Clinical Trials and Methodology, University College London, London, UK.
Paul McCroneInstitute for Life Course Development, University of Greenwich, London, UK.
Swaran P SinghMental Health and Wellbeing Warwick Medical School, University of Warwick, Coventry, UK.
Max Birchwood *Mental Health and Wellbeing Warwick Medical School, University of Warwick, Coventry, UK.
Rachel Upthegrove *Institute for Mental Health, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
University of Birmingham · GBUniversity of Warwick · GBBirmingham and Solihull Mental Health NHS Foundation Trust · GBMRC Clinical Trials Unit at UCL · GBUniversity of Bristol · GBUniversity of Cambridge · GBUniversity of East Anglia · GBUniversity of Greenwich · GBUniversity of Sussex · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePsychosis disproportionally affects ethnic minority groups in high-income countries, yet evidence of disparities in outcomes following intensive early intervention service (EIS) for First Episode Psychosis (FEP) is less conclusive. We investigated 5-year clinical and social outcomes of young people with FEP from different racial groups following EIS care.

methodData were analysed from the UK-wide NIHR SUPEREDEN study. The sample at baseline (n = 978) included White (n = 750), Black (n = 71), and Asian (n = 157) individuals, assessed during the 3 years of EIS, and up to 2 years post-discharge (n = 296; Black [n = 23]; Asian [n = 52] and White [n = 221]). Outcome trajectories were modelled for psychosis symptoms (positive, negative, and general), functioning, and depression, using linear mixed effect models (with random intercept and slopes), whilst controlling for social deprivation. Discharge service was also explored across racial groups, 2 years following EIS.

resultsVariation in linear growth over time was accounted for by racial group status for psychosis symptoms-positive (95% CI [0.679, 1.235]), negative (95% CI [0.315, 0.783]), and general (95% CI [1.961, 3.428])-as well as for functioning (95% CI [11.212, 17.677]) and depressive symptoms (95% CI [0.261, 0.648]). Social deprivation contributed to this variance. Black individuals experienced greater levels of deprivation (p < 0.001, 95% CI [0.187, 0.624]). Finally, there was a greater likelihood for Asian (OR = 3.04; 95% CI [2.050, 4.498]) and Black individuals (OR = 2.47; 95% CI [1.354, 4.520]) to remain in secondary care by follow-up.

conclusionFindings suggest variations in long-term clinical and social outcomes following EIS across racial groups; social deprivation contributed to this variance. Black and Asian individuals appear to make less improvement in long-term recovery and are less likely to be discharged from mental health services. Replication is needed in large, complete data, to fully understand disparities and blind spots to care.

Indexed as

EthnicityPsychotic DisordersAdolescentAftercareHumansMinority GroupsPatient DischargeRacial GroupsUnited KingdomDeprivationEarly psychosisEthnicityInequitiesOutcomes

Identifiers

PMID36717434
PMCPMC10066114
OpenAlexW4318577403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.