ArticleUltrasound in medicine & biology2023
Molecular Identity Changes of Tumor-Associated Macrophages and Microglia After Magnetic Resonance Imaging-Guided Focused Ultrasound-Induced Blood-Brain Barrier Opening in a Mouse Glioblastoma Model.
Erratum issuedOpen access · greenAbstract read
In one paragraph
Article in Ultrasound in medicine & biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Efficacy and safety of low- and high-intensity focused ultrasound in glioblastoma: a systematic review of preclinical and clinical studies.British journal of cancer · 2026Pooled it
- Next-generation therapeutics for glioblastoma: Challenges and future directions.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Review
- Hypothetical applications of MR-guided focused ultrasound in central nervous system tuberculosis: blood-brain barrier disruption, granulomatous lesion modulation, targeted drug delivery, and immune microenvironment reprogramming.Annals of medicine and surgery (2012) · 2026Article
- Ultrasound-Enhanced Drug Delivery in Pediatric Neuro-Oncology: A New Therapeutic Strategy.Pharmaceutics · 2026Review
- Oligodendrocyte: Development, Plasticity, Biological Functions, Diseases, and Therapeutic Targets.MedComm · 2026Review
- Reprogramming tumor-associated macrophages in DMG/DIPG: emerging molecular and biophysical strategies.Frontiers in immunology · 2026Review
- Regulation of the brain tumor microenvironment by focused ultrasound.Molecular therapy. Oncology · 2025Review
- Ultrasound-responsive nanoparticles for imaging and therapy of brain tumors.Materials today. Bio · 2025Review
- From BBB to PPP: Bioenergetic requirements and challenges for oligodendrocytes in health and disease.Journal of neurochemistry · 2025Review
- Pulsed focused ultrasound alters the proteomic profile of the tumor microenvironment in a syngeneic mouse model of glioblastoma.Journal of neuro-oncology · 2024Article
- Recurrent Glioblastoma-Molecular Underpinnings and Evolving Treatment Paradigms.International journal of molecular sciences · 2024Review
- Pulsed Low-Intensity Focused Ultrasound (LIFU) Activation of Ovarian Follicles.IEEE open journal of engineering in medicine and biology · 2024Article
- Microglia in pediatric brain tumors: The missing link to successful immunotherapy.Cell reports. Medicine · 2023Review
- Using focused ultrasound to modulate microglial structure and function.Frontiers in cellular neuroscience · 2023Review
- Glial cells: an important switch for the vascular function of the central nervous system.Frontiers in cellular neuroscience · 2023Review
- Interactions between microglia and glioma in tumor microenvironment.Frontiers in oncology · 2023Review
Corrections and comments
- Erratum issued
Authors and funding
14 authors at 8 institutions in 4 countries.
Yanrong ZhangDepartment of Radiology, Neuroradiology Division, Stanford University, Stanford, CA, USA.
Jing WangDepartment of Radiology, Neuroradiology Division, Stanford University, Stanford, CA, USA; Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Sara Natasha GhobadiDepartment of Radiology, Neuroradiology Division, Stanford University, Stanford, CA, USA.
Haiyan ZhouDepartment of Radiology, Neuroradiology Division, Stanford University, Stanford, CA, USA; Acupuncture and Tuina School/Third Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Ai HuangDepartment of Radiology, Neuroradiology Division, Stanford University, Stanford, CA, USA; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Marco GerosaDepartment of Radiology, Neuroradiology Division, Stanford University, Stanford, CA, USA; Department of Diagnostic and Public Health, University of Verona, Verona, Italy.
Qingyi HouDepartment of Radiology, Neuroradiology Division, Stanford University, Stanford, CA, USA; Department of Nuclear Medicine, Guangdong Provincial People's Hospital, Guangzhou, China.
Olivier KeunenIn Vivo Imaging Facility, Luxembourg Institute of Health, Luxembourg.
Anna GolebiewskaDepartment of Oncology, Luxembourg Institute of Health, Luxembourg.
Frezghi G HabteDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford, CA, USA.
Gerald A GrantDivision of Pediatric Neurosurgery, Department of Neurosurgery, Lucile Packard Children's Hospital, Stanford University School of Medicine, Stanford, CA, USA.
Ramasamy PaulmuruganMolecular Imaging Program at Stanford (MIPS), Canary Center for Cancer Early Detection, Department of Radiology, Stanford University, Stanford, CA, USA.
Kevin S LeeDepartments of Neuroscience and Neurosurgery and Center for Brain, Immunology, and Glia, School of Medicine, University of Virginia, Charlottesville, VA, USA.
Max WintermarkDepartment of Neuroradiology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: Max.Wintermark@gmail.com.
Stanford University · USLuxembourg Institute of Health · LUChengdu University of Traditional Chinese Medicine · CNHuazhong University of Science and Technology · CNShandong First Medical University · CNStanford Medicine · USThe University of Texas MD Anderson Cancer Center · USUniversity of Virginia · US
Funding
Translational Oncology Research Program (Project-005)P30CA124435 · NCI · STANFORD UNIVERSITY · PI Vittorio Sebastiano · 2007 to 2026
$71.4MMR-Guided Focused Ultrasound Combined with Immunotherapy to Treat Malignant Brain TumorsR01CA217953 · NCI · STANFORD UNIVERSITY · PI HEIT, JEREMY J · 2017 to 2021
$3.1MPrecise, non-invasive, axon-sparing surgery for the treatment of drug resistant epilepsyR01NS102194 · NINDS · UNIVERSITY OF VIRGINIA · PI LEE, KEVIN SCOTT · 2018 to 2022
$2.1MNCI NIH HHS P30 CA124435NCI NIH HHS R01 CA217953NINDS NIH HHS R01 NS102194
Abstract
An orthotopically allografted mouse GL26 glioma model (Ccr2
Indexed as
GlioblastomaGliomaAnimalsBlood-Brain BarrierDisease Models, AnimalMagnetic Resonance ImagingMiceMicrobubblesMicrogliaTumor-Associated MacrophagesFocused ultrasoundGlioblastomaMagnetic resonance imaging–guided focused ultrasoundMicrobubblesMicroglia and macrophage activationSterile inflammationTumor-associated macrophages and microglia
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.