Evidence map›Paper›PMID 36717142›Full record

ArticleBMJ open2023

Thromboembolic events in hospitalised patients with COVID-19: ecological assessment with a scoping review.

Saori Kurata, Naoki Miyayama, Kenta Ogawa, Kaede Watanabe, Kengo Asano, Tomoko Fujii

Open access · goldAbstract readScoping Review
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 3 countries.

Saori KurataDepartment of Emergency Care Center, Saiseikai Yokohamashi Tobu Hospital, Yokohama, Kanagawa, Japan.
Naoki MiyayamaIntensive Care Unit, Jikei University Hospital, Tokyo, Japan.
Kenta OgawaIntensive Care Unit, Jikei University Hospital, Tokyo, Japan.
Kaede WatanabeIntensive Care Unit, Jikei University Hospital, Tokyo, Japan.
Kengo AsanoIntensive Care Unit, Jikei University Hospital, Tokyo, Japan.
Tomoko FujiiIntensive Care Unit, Jikei University Hospital, Tokyo, Japan tofujii-tky@umin.net.ORCID 0000-0003-3854-4081
Intensive Care Society · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThrombosis is a common complication of the novel COVID-19. Pre-COVID-19 studies reported racial differences in the risk of developing thrombosis. This study aimed to describe the geographical variations in the reported incidences and outcomes of thromboembolic events and thromboprophylaxis in hospitalised patients with COVID-19. The final search for randomised clinical trials was carried out in January 2022. Screening eligible articles and data extraction were independently performed in duplicate by multiple reviewers.

designScoping review. MEDLINE, Embase, Cochrane Libraries were searched using terms related to COVID-19 and thromboembolism.

settingHospitals all over the world.

participantsIn-hospital patients with COVID-19. OUTCOME MEASURES: The incidence of deep venous thrombosis (DVT) and pulmonary embolism (PE), and the prophylactic anticoagulation therapy.

resultsIn total, 283 studies were eligible, representing (239 observational studies, 39 case series and 7 interventional studies). The incidence of DVT was the highest in Asia (40.8%) and hospital mortality was high (22.7%). However, the incidence of PE was not very high in Asia (3.2%). On the contrary, the incidence of PE was the highest in the Middle East (16.2%) and Europe (14. 6%). Prophylactic anticoagulation therapy with low-molecular-weight heparin was the main treatment provided in all areas. Four of the seven randomised clinical trials were conducted internationally.

conclusionsThe incidence of DVT was the highest in Asia. The incidence of PE was higher in the Middle East and Europe; however, detection bias during the pandemic cannot be ruled out. There were no major differences in the type or dose of prophylactic anticoagulants used for thromboprophylaxis among the regions.

Indexed as

COVID-19Pulmonary EmbolismThrombosisVenous ThromboembolismVenous ThrombosisAnticoagulantsHumansAnticoagulantsAnticoagulationCOVID-19INTENSIVE & CRITICAL CAREThromboembolism

Identifiers

PMID36717142
PMCPMC9887473
OpenAlexW4318671856

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.