Evidence map›Paper›PMID 36716516›Full record

ArticleBioelectrochemistry (Amsterdam, Netherlands)2023

Molecularly imprinted miniature electrochemical biosensor for SARS-CoV-2 spike protein based on Au nanoparticles and reduced graphene oxide modified acupuncture needle.

Xu Yang, Zheng-Zhi Yin, Guojun Zheng, Min Zhou, Hongyu Zhang, Junyao Li, Wenrong Cai, Yong Kong

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioelectrochemistry (Amsterdam, Netherlands), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Xu YangJiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China.
Zheng-Zhi YinCollege of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing 314001, China. Electronic address: yinzhengzhi@zjxu.edu.cn.
Guojun ZhengDepartment of Clinical Laboratory, Changzhou No.3 People's Hospital, Changzhou 213001, China.
Min ZhouDepartment of Clinical Laboratory, Changzhou No.3 People's Hospital, Changzhou 213001, China.
Hongyu ZhangDepartment of Clinical Laboratory, Changzhou No.3 People's Hospital, Changzhou 213001, China.
Junyao LiJiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China.
Wenrong CaiJiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China; Shandong Key Laboratory of Biochemical Analysis, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
Yong KongJiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China. Electronic address: yzkongyong@cczu.edu.cn.
Changzhou No.2 People's Hospital · CNChangzhou University · CNJiangsu University of Technology · CNJiaxing University · CNQingdao University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate detection of SARS-CoV-2 spike (SARS-CoV-2-S) protein is of clinical significance for early diagnosis and timely treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Herein, a surface molecularly imprinted miniature biosensor was fabricated. Au nanoparticles (AuNPs), reduced graphene oxide (rGO), poly(methylene blue)/poly(ionic liquids) and poly(ionic liquids) were successively electrodeposited onto the pinpoint of an acupuncture needle (AN). The molecularly imprinted miniature biosensor was obtained after the template of SARS-CoV-2-S protein was removed, which could be used for sensitive detection of SARS-CoV-2-S protein. The linear range and limit of detection (LOD) were 0.1 ∼ 1000 ng mL

Indexed as

Acupuncture TherapyBiosensing TechniquesCOVID-19Ionic LiquidsMetal NanoparticlesMolecular ImprintingElectrochemical TechniquesElectrodesGoldGraphiteHumansReproducibility of ResultsSARS-CoV-2Spike Glycoprotein, CoronavirusGoldgraphene oxideGraphiteIonic LiquidsSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2Acupuncture needleMiniature electrochemical biosensorMolecular imprintingPoly(ionic liquids)SARS-CoV-2 spike protein

Identifiers

PMID36716516
PMCPMC9883973
OpenAlexW4318204181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.