Evidence map›Paper›PMID 36715638›Full record

Trial reportPain medicine (Malden, Mass.)2023

A 4-week morning light treatment with stable sleep timing for individuals with fibromyalgia: a randomized controlled trial.

Helen J Burgess, Sonal Bahl, Katelyn Wilensky, Emily Spence, Riley J Jouppi, Muneer Rizvydeen, Cathy Goldstein, Hyungjin Myra Kim, David A Williams, John W Burns

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Pain medicine (Malden, Mass.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Helen J BurgessDepartment of Psychiatry, University of Michigan, Ann Arbor, MI 48109, United States.ORCID 0000-0003-3816-8194
Sonal BahlDepartment of Psychiatry, University of Michigan, Ann Arbor, MI 48109, United States.
Katelyn WilenskyDepartment of Psychiatry, University of Michigan, Ann Arbor, MI 48109, United States.
Emily SpenceDepartment of Psychiatry, University of Michigan, Ann Arbor, MI 48109, United States.
Riley J JouppiDepartment of Psychiatry, University of Michigan, Ann Arbor, MI 48109, United States.
Muneer RizvydeenDepartment of Psychiatry, University of Michigan, Ann Arbor, MI 48109, United States.
Cathy GoldsteinDepartment of Neurology, University of Michigan, Ann Arbor, MI 48109, United States.
Hyungjin Myra KimDepartment of Biostatistics, University of Michigan, Ann Arbor, MI 48109, United States.
David A WilliamsDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, United States.
John W BurnsDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL 60612, United States.
University of Michigan · USRush University Medical Center · US

Funding

Bright Light Treatment At Home To Improve Symptom Management of Fibromyalgia SyndromeR21NR016930 · NINR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BURGESS, HELEN JULIA, BURNS, JOHN W. · 2018 to 2019
$422k
NINR NIH HHS R21 NR016930
6 · The paper itself

Abstract

objectivesFibromyalgia is characterized by chronic widespread pain, mood, and sleep disturbance. Pharmacological treatments have modest efficacy and are associated with negative side effects, and alternative approaches are needed. Morning bright light treatment may assist in the management of fibromyalgia as it can reduce depressive symptoms, improve sleep, and advance circadian timing.

methodsSixty people with fibromyalgia (58 women, mean age 41.8 ± 13.3 years) were enrolled in a study comparing 4 weeks of a 1-hour daily morning bright light treatment (active treatment) to a morning dim light treatment (comparison treatment). Both light treatments included behavioral procedures to stabilize sleep timing. The morning bright light treatment was expected to produce larger improvements in pain and function than the dim light treatment and larger improvements in potential mediators (mood, sleep, and circadian timing).

resultsBoth the bright and dim light treatment groups achieved significant but similar levels of improvement in pain intensity, pain interference, physical function, depressive symptoms, and sleep disturbance. Overall, the sample on average displayed a clinically meaningful improvement in the Fibromyalgia Impact Questionnaire-Revised score (mean reduction of 11.2 points), comparable to that reported following physical exercise treatments. Minimal side effects were observed.

conclusionsFindings indicate that the effects of a morning bright light treatment did not exceed those of a comparison dim light treatment; yet the changes on average in both conditions revealed clinically meaningful improvements. Future research is warranted to identify what elements of this trial may have contributed to the observed effects.

Indexed as

Chronic PainFibromyalgiaAdultCircadian RhythmFemaleHumansMiddle AgedPhototherapySleepSurveys and Questionnairesactigraphyfibromyalgiamorning lightsleep

Identifiers

PMID36715638
PMCPMC10321765
OpenAlexW4318541224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.