Evidence map›Paper›PMID 36715542›Full record

ReviewJournal of bacteriology2023

Synchronized Swarmers and Sticky Stalks: Caulobacter crescentus as a Model for Bacterial Cell Biology.

Jordan M Barrows, Erin D Goley

Open access · greenAbstract readReview
In one paragraph

Review in Journal of bacteriology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 48 citations in OpenAlex.

  1. The complete genome sequence ofMicrobiology resource announcements · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. An N4-likeJournal of bacteriology · 2026
    Article
  6. An activator of a two-component system controls cell separation and intrinsic drug resistance inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
  8. Electron Cryo-Tomography Reveals thebioRxiv : the preprint server for biology · 2025
    Article
  9. An N4-likebioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. TheJournal of bacteriology · 2024
    Article
  18. Hitchhiker's Guide toJournal of bacteriology · 2024
    Review
  19. Article
  20. GTPase activity regulates FtsZ ring positioning inMolecular biology of the cell · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jordan M BarrowsDepartment of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-9693-0207
Erin D GoleyDepartment of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-8518-2303
Johns Hopkins University · US

Funding

BIOCHEMISTRY, CELLULAR AND MOLECULAR BIOLOGY PROGRAMT32GM007445 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GREEN, RACHEL · 1985 to 2021
$24.1M
Local and global regulation of bacterial growthR35GM136221 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Erin D Goley · 2020 to 2026
$3.0M
NIGMS NIH HHS R35 GM136221NIGMS NIH HHS T32 GM007445
6 · The paper itself

Abstract

First isolated and classified in the 1960s, Caulobacter crescentus has been instrumental in the study of bacterial cell biology and differentiation. C. crescentus is a Gram-negative alphaproteobacterium that exhibits a dimorphic life cycle composed of two distinct cell types: a motile swarmer cell and a nonmotile, division-competent stalked cell. Progression through the cell cycle is accentuated by tightly controlled biogenesis of appendages, morphological transitions, and distinct localization of developmental regulators. These features as well as the ability to synchronize populations of cells and follow their progression make C. crescentus an ideal model for answering questions relevant to how development and differentiation are achieved at the single-cell level. This review will explore the discovery and development of C. crescentus as a model organism before diving into several key features and discoveries that have made it such a powerful organism to study. Finally, we will summarize a few of the ongoing areas of research that are leveraging knowledge gained over the last century with C. crescentus to highlight its continuing role at the forefront of cell and developmental biology.

Indexed as

Caulobacter crescentusBacterial ProteinsCell CycleCell DivisionBacterial Proteinsbacterial cell biologyCaulobacterCaulobacter crescentuscell cycledifferentiationmodel organismmorphogenesis

Identifiers

PMID36715542
PMCPMC9945503
OpenAlexW4318482186

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.