Evidence map›Paper›PMID 36715424›Full record

ArticleAmerican journal of hematology2023

Factor H autoantibodies contribute to complement dysregulation in multisystem inflammatory syndrome in children (MIS-C).

Patricia E Zerra, Jennifer Stowell, Hans Verkerke, James McCoy, Jayre Jones, Sara Graciaa, Austin Lu, Laila Hussaini, Evan J Anderson, Christina A Rostad and 2 more

Abstract readLetter
In one paragraph

Article in American journal of hematology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Patricia E ZerraCenter for Transfusion Medicine and Cellular Therapies, Department of Laboratory Medicine and Pathology, Emory University, Atlanta, Georgia, USA.
Jennifer StowellSchool of Public Health, Boston University, Boston, Massachusetts, USA.ORCID 0000-0001-6879-7149
Hans VerkerkeCenter for Transfusion Medicine and Cellular Therapies, Department of Laboratory Medicine and Pathology, Emory University, Atlanta, Georgia, USA.
James McCoyCenter for Transfusion Medicine and Cellular Therapies, Department of Laboratory Medicine and Pathology, Emory University, Atlanta, Georgia, USA.
Jayre JonesAflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA.
Sara GraciaaAflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA.
Austin LuDivision of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Laila HussainiDivision of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Evan J AndersonDivision of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Christina A RostadDivision of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Sean R StowellJoint Program in Transfusion Medicine, Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.
Satheesh ChonatAflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA.ORCID 0000-0002-5909-0800

Funding

Medical Scientist Training ProgramT32GM142617 · NIGMS · EMORY UNIVERSITY · PI Jason Yustein · 2022 to 2026
$7.0M
Atlanta Pediatric Scholars ProgramK12HD072245 · NICHD · EMORY UNIVERSITY · PI Shari Barkin · 2012 to 2026
$5.5M
Engineering iPSC-RBCs for TransfusionR01HL138656 · NHLBI · EMORY UNIVERSITY · PI ROBACK, JOHN D, STOWELL, SEAN R · 2017 to 2020
$2.9M
Examination of Initiating Factors that Regulate Red Blood Cell AlloimmunizationR01HL135575 · NHLBI · EMORY UNIVERSITY · PI Sean R Stowell · 2017 to 2026
$2.8M
NHLBI NIH HHS R01 HL135575NHLBI NIH HHS R01 HL138656NICHD NIH HHS K12 HD072245NIGMS NIH HHS T32 GM142617
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Complement Factor HSystemic Inflammatory Response SyndromeChildCOVID-19HumansComplement Factor H

Identifiers

PMID36715424
PMCPMC10089943

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.