Evidence map›Paper›PMID 36715100›Full record

ArticleeLife2023

Geometric control of myosin II orientation during axis elongation.

Matthew F Lefebvre, Nikolas H Claussen, Noah P Mitchell, Hannah J Gustafson, Sebastian J Streichan

Abstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. The role of geometry in morphogenesis.Development (Cambridge, England) · 2026
    Review
  2. Article
  3. bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. A model for boundary-driven tissue morphogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Myosin 2 - A general contractor for the cytoskeleton.Current opinion in cell biology · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Stochastic morphological swings inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Article
  13. Article
  14. The Geometric Basis of Epithelial Convergent Extension.bioRxiv : the preprint server for biology · 2024
    Article
  15. Article
  16. Article
  17. Patterning of morphogenetic anisotropy fields.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matthew F Lefebvre *Department of Physics, University of California, Santa Barbara, Santa Barbara, United States.ORCID 0000-0002-9590-4293
Nikolas H Claussen *Department of Physics, University of California, Santa Barbara, Santa Barbara, United States.ORCID 0000-0002-9020-6437
Noah P MitchellDepartment of Physics, University of California, Santa Barbara, Santa Barbara, United States.
Hannah J GustafsonDepartment of Physics, University of California, Santa Barbara, Santa Barbara, United States.
Sebastian J StreichanDepartment of Physics, University of California, Santa Barbara, Santa Barbara, United States.ORCID 0000-0002-6105-9087

Funding

Physics of Living Matter: From Molecule to Embryo.R35GM138203 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI Sebastian J Streichan · 2020 to 2026
$2.7M
Integration of orthogonal patterning information is necessary for regulating form during Drosophila body axis elongation: Towards an understanding of how genetic fate controls embryonic shapeF31HD093377 · NICHD · PRINCETON UNIVERSITY · PI LEFEBVRE, MATTHEW F · 2017 to 2018
$89k
NICHD NIH HHS F31 HD093377NIGMS NIH HHS R35 GM138203NIH HHS 5 R35 GM138203
6 · The paper itself

Abstract

The actomyosin cytoskeleton is a crucial driver of morphogenesis. Yet how the behavior of large-scale cytoskeletal patterns in deforming tissues emerges from the interplay of geometry, genetics, and mechanics remains incompletely understood. Convergent extension in

Indexed as

Drosophila melanogasterDrosophila ProteinsAnimalsCytoskeletal ProteinsEmbryo, NonmammalianMorphogenesisMyosinsMyosin Type IICytoskeletal ProteinsDrosophila ProteinsMyosinsMyosin Type IIaxis elongationD. melanogastermorphogenesisphysics of living systemsquantitative biology

Identifiers

PMID36715100
PMCPMC9940909

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.