Evidence map›Paper›PMID 36715006›Full record

ReviewStroke2023

Stroke Learning Health Systems: A Topical Narrative Review With Case Examples.

Dominique A Cadilhac, Dawn M Bravata, Janet Prvu Bettger, Robert Mikulik, Bo Norrving, Ezinne O Uvere, Mayowa Owolabi, Annemarei Ranta, Monique F Kilkenny

Open access · greenAbstract readReview
In one paragraph

Review in Stroke, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Hyper-Acute Stroke Systems of Care and Workflow.Current neurology and neuroscience reports · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Addressing Disparities in Acute Stroke Management and Prognosis.Journal of the American Heart Association · 2024
    Review
  13. Article
  14. Article
  15. Knowledge is power.The Lancet regional health. Southeast Asia · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 6 countries.

Dominique A CadilhacStroke and Ageing Research, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia (D.A.C., M.F.K.).ORCID 0000-0001-8162-682X
Dawn M BravataCenter for Health Information and Communication, Richard L. Roudebush VA Medical Center, Indianapolis, IN (D.M.B.).ORCID 0000-0002-3048-2536
Janet Prvu BettgerDepartment of Health and Rehabilitation Sciences, Temple University College of Public Health, Philadelphia, PA (J.P.B.).ORCID 0000-0001-9708-8413
Robert MikulikInternational Clinical Research Centre, Neurology Department, St. Ann's University Hospital and Masaryk University, Brno, Czech Republic (R.M.).ORCID 0000-0002-7458-5166
Bo NorrvingLund University, Department of Clinical Sciences Lund, Neurology, Skåne University Hospital, Sweden (B.N.).ORCID 0000-0002-8024-5096
Ezinne O UvereDepartment of Medicine, College of Medicine, University of Ibadan, Nigeria (E.O.U., M.O.).ORCID 0000-0003-3290-6483
Mayowa OwolabiDepartment of Medicine, College of Medicine, University of Ibadan, Nigeria (E.O.U., M.O.).ORCID 0000-0003-1146-3070
Annemarei RantaDepartment of Medicine, University of Otago, Wellington, New Zealand (A.R.).ORCID 0000-0002-3223-3330
Monique F KilkennyStroke and Ageing Research, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia (D.A.C., M.F.K.).ORCID 0000-0002-3375-287X
Florey Institute of Neuroscience and Mental Health · AUUniversity of Ibadan · NGMasaryk University · CZRegenstrief Institute · USSkåne University Hospital · SETemple University · USUniversity of Otago · NZ

Funding

H3Africa Administrative Coordinating Centre: Enabling and Supporting Genomics and Health Research Capacity Building in AfricaU24HG009780 · NHGRI · UNIVERSITY OF CAPE TOWN · PI SKELTON, MICHELLE · 2017 to 2022
$4.8M
Stroke Investigative Research & Educational Network (SIREN)U54HG007479 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2013 to 2017
$4.2M
CNV And Stroke (CaNVAS)R01NS114045 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI COLE, JOHN W. · 2020 to 2024
$2.6M
African Rigorous Innovative Stroke Epidemiological Surveillance (ARISES)R01NS115944 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2020 to 2025
$2.2M
Systematic Investigation of Blacks with Stroke - Genomics (SIBS-Genomics) StudyR01NS107900 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2018 to 2021
$1.8M
Training Africans to Lead and Execute Neurological Trials & Studies (TALENTS)D43TW012030 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI OVBIAGELE, BRUCE · 2021 to 2025
$1.2M
Sub-Saharan Africa Conference on Stroke (SSACS) ConferenceR13NS115395 · NINDS · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI OVBIAGELE, BRUCE · 2020 to 2020
$50k
FIC NIH HHS D43 TW012030NHGRI NIH HHS U24 HG009780NHGRI NIH HHS U54 HG007479NINDS NIH HHS R01 NS107900NINDS NIH HHS R01 NS114045NINDS NIH HHS R01 NS115944NINDS NIH HHS R13 NS115395
6 · The paper itself

Abstract

To our knowledge, the adoption of Learning Health System (LHS) concepts or approaches for improving stroke care, patient outcomes, and value have not previously been summarized. This topical review provides a summary of the published evidence about LHSs applied to stroke, and case examples applied to different aspects of stroke care from high and low-to-middle income countries. Our attempt to systematically identify the relevant literature and obtain real-world examples demonstrated the dissemination gaps, the lack of learning and action for many of the related LHS concepts across the continuum of care but also elucidated the opportunity for continued dialogue on how to study and scale LHS advances. In the field of stroke, we found only a few published examples of LHSs and health systems globally implementing some selected LHS concepts, but the term is not common. A major barrier to identifying relevant LHS examples in stroke may be the lack of an agreed taxonomy or terminology for classification. We acknowledge that health service delivery settings that leverage many of the LHS concepts do so operationally and the lessons learned are not shared in peer-reviewed literature. It is likely that this topical review will further stimulate the stroke community to disseminate related activities and use keywords such as learning health system so that the evidence base can be more readily identified.

Indexed as

Learning Health SystemStrokeHumansemergency medical servicesischemic attack, transientlearning health systemquality improvementstroke

Identifiers

PMID36715006
PMCPMC10050099
OpenAlexW4318476992

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.