Evidence map›Paper›PMID 36714848›Full record

ArticlePNAS nexus2022

Extracellular vesicle fusion visualized by cryo-electron microscopy.

Mattia I Morandi, Petro Busko, Efrat Ozer-Partuk, Suman Khan, Giulia Zarfati, Yael Elbaz-Alon, Paula Abou Karam, Tina Napso Shogan, Lana Ginini, Ziv Gil and 2 more

Abstract read
In one paragraph

Article in PNAS nexus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

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  13. p.N370SInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mattia I MorandiDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.ORCID https://orcid.org/0000-0001-8467-4552
Petro BuskoDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.
Efrat Ozer-PartukDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.
Suman KhanDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.
Giulia ZarfatiDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.
Yael Elbaz-AlonDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.
Paula Abou KaramDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.
Tina Napso ShoganFaculty of Health, Bar Ilan University, Ramat-Gan 5290002, Israel.
Lana GininiFaculty of Health, Bar Ilan University, Ramat-Gan 5290002, Israel.
Ziv GilFaculty of Health, Bar Ilan University, Ramat-Gan 5290002, Israel.
Neta Regev-RudzkiDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.
Ori AvinoamDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.ORCID https://orcid.org/0000-0003-3543-168X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) transfer bioactive molecules between cells in a process reminiscent of enveloped viruses. EV cargo delivery is thought to occur by protein-mediated and pH-dependent membrane fusion of the EV and the cellular membrane. However, there is a lack of methods to identify the fusion proteins and resolve their mechanism. We developed and benchmarked an

Identifiers

PMID36714848
PMCPMC9802263

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.