Evidence map›Paper›PMID 36714596›Full record

ReviewFrontiers in endocrinology2022

(Thyroid) Hormonal regulation of breast cancer cells.

Aleck Hercbergs, Hung-Yun Lin, Shaker A Mousa, Paul J Davis

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aleck HercbergsDepartment of Radiation Oncology, The Cleveland Clinic, Cleveland, OH, United States.
Hung-Yun LinProgram for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Shaker A MousaAlbany College of Pharmacy and Health Sciences, Albany, NY, United States.
Paul J DavisDepartment of Medicine, Albany Medical College, Albany, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid hormone as L-thyroxine (T4) acts nongenomically at physiological concentrations at its cancer cell surface receptor on integrin αvβ3 ('thyrointegrin') to cause cancer cell proliferation. In the case of estrogen receptor (ERα)-positive breast cancer cells, T4

Indexed as

Breast NeoplasmsThyroid GlandEstrogen Receptor alphaFemaleHumansThyroid HormonesThyroxineEstrogen Receptor alphaThyroid HormonesThyroxine33’-triiodo-L-thyronine(T3)5breast cancerestrogen receptor-α (ERα)euthyroid hypothyroxinemiaintegrin αvβ3L-thyroxine (T4)

Identifiers

PMID36714596
PMCPMC9874134

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.