Evidence map›Paper›PMID 36714457›Full record

ArticleNeurology and clinical neuroscience2023

Neurological manifestations in SARS-CoV-2 infection: A single-center cross-sectional study in Malaysia.

Hui Jan Tan, Cheon Han Goh, Ching Soong Khoo, Chen Fei Ng, Juen Kiem Tan, Wan Asyraf Wan Zaidi, Zhe Kang Law, Muhamad Danial Zulkifli, Shahrul Azmin Md Rani, Wan Nur Nafisah Wan Yahya and 7 more

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In one paragraph

Article in Neurology and clinical neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Hui Jan TanDepartment of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Cheon Han GohDepartment of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Ching Soong KhooDepartment of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.ORCID https://orcid.org/0000-0002-6756-0411
Chen Fei NgDepartment of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Juen Kiem TanDepartment of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Wan Asyraf Wan ZaidiDepartment of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Zhe Kang LawDepartment of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Muhamad Danial ZulkifliDepartment of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Shahrul Azmin Md RaniDepartment of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Wan Nur Nafisah Wan YahyaDepartment of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Rabani RemliDepartment of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Norlinah Mohamed IbrahimDepartment of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Rozita HodDepartment of Community Health, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Shahizon Azura Mohamed MukariDepartment of Radiology, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Aida-Widure Mustapha Mohd MustaphaDepartment of Radiology, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Najma KoriDepartment of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
Petrick PeriyasamyDepartment of Medicine, Faculty of Medicine The National University of Malaysia Kuala Lumpur Malaysia.
National University of Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Neurological involvement associated with SARS-CoV-2 infection has been reported from different regions of the world. However, data from South East Asia are scarce. We described the neurological manifestations and their associated factors among the hospitalized COVID-19 patients from an academic tertiary hospital in Malaysia. Methods: A cross-sectional observational study of hospitalized COVID-19 patients was conducted. The neurological manifestations were divided into the self-reported central nervous system (CNS) symptoms, stroke associated symptoms, symptoms of encephalitis or encephalopathy and specific neurological complications. Multiple logistic regression was performed using demographic and clinical variables to determine the factors associated with outcome. Results: Of 156 hospitalized COVID-19 patients with mean age of 55.88 ± 6.11 (SD) years, 23.7% developed neurological complications, which included stroke, encephalitis and encephalopathy. Patients with neurological complications were more likely to have diabetes mellitus ( Conclusions: Stroke, encephalitis and encephalopathy were the common neurological complications from our study. Diabetes mellitus, presence of symptoms of stroke, symptoms of encephalitis or encephalopathy, leukocytosis, and being unvaccinated against COVID-19 were the associated risk factors of developing neurological complications.

Indexed as

encephalitisencephalopathyneurological manifestationsSARS‐CoV‐2stroke

Identifiers

PMID36714457
PMCPMC9874463
OpenAlexW4307037630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.