Evidence map›Paper›PMID 36714234›Full record

ArticleCurrent urology2022

Prostate cancer screening: Continued controversies and novel biomarker advancements.

Atiyah Tidd-Johnson, Sneha Annie Sebastian, Edzel Lorraine Co, Munaza Afaq, Hansini Kochhar, Mona Sheikh, Arpit Mago, Sujan Poudel, John A Fernandez, Ivan D Rodriguez and 1 more

Abstract read
In one paragraph

Article in Current urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Targeting prostate adenocarcinoma tumor microenvironment via cancer nanotheranostics: a comprehensive update on improved roadmap for disease diagnosis, therapy and management.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Possible Roles for Purinergic Receptor P2RX4 in Breast and Prostate Cancers.International journal of molecular sciences · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Atiyah Tidd-JohnsonDivision of Research & Academic Affairs, Larkin Community Hospital, South Miami, FL, USA.
Sneha Annie SebastianDivision of Research & Academic Affairs, Larkin Community Hospital, South Miami, FL, USA.
Edzel Lorraine CoDivision of Research & Academic Affairs, Larkin Community Hospital, South Miami, FL, USA.
Munaza AfaqDivision of Research & Academic Affairs, Larkin Community Hospital, South Miami, FL, USA.
Hansini KochharDivision of Research & Academic Affairs, Larkin Community Hospital, South Miami, FL, USA.
Mona SheikhDivision of Research & Academic Affairs, Larkin Community Hospital, South Miami, FL, USA.
Arpit MagoDivision of Research & Academic Affairs, Larkin Community Hospital, South Miami, FL, USA.
Sujan PoudelDivision of Research & Academic Affairs, Larkin Community Hospital, South Miami, FL, USA.
John A FernandezDivision of Research & Academic Affairs, Larkin Community Hospital, South Miami, FL, USA.
Ivan D RodriguezDivision of Research & Academic Affairs, Larkin Community Hospital, South Miami, FL, USA.
Sanjay RazdanDivision of Research & Academic Affairs, Larkin Community Hospital, South Miami, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) screening remains one of the most controversial topics in clinical and public health. Despite being the second most common cancer in men worldwide, recommendations for screening using prostate-specific antigen (PSA) are unclear. Early detection and the resulting postscreening treatment lead to overdiagnosis and overtreatment of otherwise indolent cases. In addition, several unwanted harms are associated with PCa screening process. This literature review focuses on the limitations of PSA-specific PCa screening, reasons behind the screening controversy, and the novel biomarkers and advanced innovative methodologies that improve the limitations of traditional screening using PSA. With the verdict of whether or not to screen not yet unanimous, we hope to aid in resolution of the long-standing debate.

Indexed as

BiopsyLiquid biopsyMultiparametric magnetic resonance imagingNovel biomarkersProstate cancerProstate cancer screeningProstate-specific antigenTumor markers

Identifiers

PMID36714234
PMCPMC9875204

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.