Evidence map›Paper›PMID 36714224›Full record

ArticleIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India2023

Upper Airway Mucociliary Clearance is Impaired in Dyspneic COVID-19 Patients.

Rogério Pezato, Andrea Goldwasser David, Alexandre Coelho Boggi, Bruna Melo, Claudia Maria Valete Rosalino, Athenea Pascual Rodriguez, Andrew Thamboo, Richard Louis Voegels

Open access · bronzeAbstract read
In one paragraph

Article in Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Rogério PezatoAv. Prof. Lineu Prestes, 2565 - Butantã, São Paulo, SP 05508-000 Brazil Departament of Ophathalmology and Otorhinolaryngology, University of Sao Paulo.ORCID 0000-0002-9813-4466
Andrea Goldwasser DavidVancouver, BC Canada Centre of Heart Lung Innovation, University of British Columbia.
Alexandre Coelho BoggiSão Paulo, Brazil Department of Otorhinolaryngology and Head and Neck Surgery, Universidade Federal de São Paulo.
Bruna MeloAv. Brasil, 4365 - Manguinhos, Rio de Janeiro, RJ 21040-900 Brazil Fundação Oswaldo Cruz.
Claudia Maria Valete RosalinoAv. Brasil, 4365 - Manguinhos, Rio de Janeiro, RJ 21040-900 Brazil Fundação Oswaldo Cruz.
Athenea Pascual RodriguezVancouver, BC Canada Centre of Heart Lung Innovation, University of British Columbia.
Andrew ThambooVancouver, BC Canada Centre of Heart Lung Innovation, University of British Columbia.
Richard Louis VoegelsAv. Prof. Lineu Prestes, 2565 - Butantã, São Paulo, SP 05508-000 Brazil Departament of Ophathalmology and Otorhinolaryngology, University of Sao Paulo.
University of British Columbia · CAFundação Oswaldo Cruz · BRHospital Central da Polícia Militar · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Covid-19 is transmitted mainly by respiratory droplets and as the upper airway mucosa is the first innate immune barrier, it is crucial to understand the effects of SARS-CoV-2 on this system. In the current study, we aimed to evaluate the nasal mucociliary clearance in patients with SARS-CoV-2 infection and their symptom development. Observational cross-sectional study. The nasal mucociliary clearance (NMC) time was evaluated by the saccharin test and the results were compared between patients with SARS-CoV-2 infection (group 1) and controls (group 2, asymptomatic patients with a negative polymerase chain reaction test). We also compared the NMC time for each specific symptom suffered by participants in group 1 with the NMC time of the control group as well as with the patients in group 1 who were asymptomatic. There was a significant increase in NMC time in group 1 with dyspnea when compared to the control group (

Indexed as

AnosmiaCOVID-19Mucociliary clearanceSaccharinSARS-CoV-2

Identifiers

PMID36714224
PMCPMC9867881
OpenAlexW4317436595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.