Evidence map›Paper›PMID 36714140›Full record

ArticleFrontiers in medicine2022

Clinical characteristics, risk factors and diagnostic outcomes of patients presented with indeterminate biliary stricture: A multicenter study.

Mohammed Tag-Adeen, Mohamed Malak, Muhammad Abdel-Gawad, Ahmed Abu-Elfatth, Ramadan H Eldamarawy, Ahmed Alzamzamy, Mohamed Elbasiony, Ramy M Elsharkawy, Fathiya El-Raey, Ahmed N Basiony and 13 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
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Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 8 institutions in 1 country.

Mohammed Tag-AdeenDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Qena Faculty of Medicine, South Valley University, Qena, Egypt.
Mohamed MalakDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Faculty of Medicine, Sohag University, Sohag, Egypt.
Muhammad Abdel-GawadHepatology, Gastroenterology, and Infectious Diseases, Al-Azhar University, Assiut, Egypt.
Ahmed Abu-ElfatthDepartment of Tropical Medicine and Gastroenterology, Assuit University, Assiut, Egypt.
Ramadan H EldamarawyDepartment of Internal Medicine, Al-Azhar University, Cairo, Egypt.
Ahmed AlzamzamyDepartment of Gastroenterology and Heptology, Maadi Armed Forces Medical Complex, Military Medical Academy, Cairo, Egypt.
Mohamed ElbasionyDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Faculty of Medicine, Mansoura University, Mansoura, Dakahlya, Egypt.
Ramy M ElsharkawyDepartment of Tropical Medicine and Gastroenterology, Faculty of Medicine, Sohag University, Sohag, Egypt.
Fathiya El-RaeyDepartment of Hepatogastroenterology and Infectious Diseases, Al-Azhar University, Damietta, Egypt.
Ahmed N BasionyDepartment of Tropical Medicine, Ain Shams University, Cairo, Egypt.
Ahmed QasemHepatology, Gastroenterology, and Infectious Diseases, Al-Azhar University, Assiut, Egypt.
Zakarya ShadyDepartment of Internal Medicine, Al-Azhar University, Cairo, Egypt.
Ahmed S AbdelmohsenDepartment of Tropical Medicine and Gastroenterology, Assuit University, Assiut, Egypt.
Doaa AbdeltawabDepartment of Tropical Medicine and Gastroenterology, Assuit University, Assiut, Egypt.
Mahmoud FaroukDepartment of Tropical Medicine and Gastroenterology, Assuit University, Assiut, Egypt.
Ola M FouadDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Qena Faculty of Medicine, South Valley University, Qena, Egypt.
Ahmed RabieDepartment of Pathology, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Abdul-Hakim ErianDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Qena Faculty of Medicine, South Valley University, Qena, Egypt.
Ahlam SapraDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Qena Faculty of Medicine, South Valley University, Qena, Egypt.
Wael Shaibat-AlhamdDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Al-Azhar Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Ashraf AboubakrDepartment of Gastroenterology and Heptology, Maadi Armed Forces Medical Complex, Military Medical Academy, Cairo, Egypt.
Dalia OmranDepartment of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Giza, Egypt.
Mohamed AlboraieDepartment of Internal Medicine, Al-Azhar University, Cairo, Egypt.
Al-Azhar University · EGAssiut University · EGSouth Valley University · EGMilitary Medical Academy · EGSohag University · EGAin Shams University · EGCairo University · EGMansoura University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: Indeterminate biliary stricture (IBS) is a frequently encountered clinical problem. In this study, we aimed to highlight the clinical characteristics, risk factors and diagnostic outcomes of patients presented with indeterminate biliary stricture. Method: A Retrospective multicenter study included all patients diagnosed with IBS in the participating centers between 2017 and 2021. Data regarding IBS such as presentations, patient characteristics, diagnostic and therapeutic modalities were collected from the patients' records and then were analyzed. Results: Data of 315 patients with IBS were retrospectively collected from 7 medical centers with mean age: 62.6 ± 11 years, females: 40.3% and smokers: 44.8%. For diagnosing stricture; Magnetic resonance imaging/Magnetic resonance cholangiopancreatography (MRI/MRCP) was the most frequently requested imaging modality in all patients, Contrast enhanced computerized tomography (CECT) in 85% and endoscopic ultrasound (EUS) in 23.8%. Tissue diagnosis of cholangiocarcinoma was achieved in 14% only. The used therapeutic modalities were endoscopic retrograde cholangiopancreatography (ERCP)/stenting in 70.5%, percutaneous trans-hepatic biliary drainage (PTD): 17.8%, EUS guided drainage: 0.3%, and surgical resection in 8%. The most frequent type of strictures was distal stricture in 181 patients, perihilar in 128 and intrahepatic in 6. Distal strictures had significant male predominance, with higher role for EUS for diagnosis and higher role for ERCP/stenting for drainage, while in the perihilar strictures, there was higher role for CECT and MRI/MRCP for diagnosis and more frequent use of PTD for drainage. Conclusion: Indeterminate biliary stricture is a challenging clinical problem with lack of tissue diagnosis in most of cases mandates an urgent consensus diagnostic and treatment guidelines.

Indexed as

biliary strictureCECTcholangiocarcinoma (CCA)ERCPMRCPMRI

Identifiers

PMID36714140
PMCPMC9875376
OpenAlexW4313985056

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