Evidence map›Paper›PMID 36714065›Full record

ArticleBlood cell therapy2021

HEMATOPOIETIC STEM CELL TRANSPLANT IN AGGRESSIVE T AND NK/T CELL LYMPHOMA - ROLE OF UPFRONT AUTOLOGOUS TRANSPLANT IN NODAL PERIPHERAL T-CELL LYMPHOMA.

Lawrence Cheng Kiat Ng, Christopher Shwei Wen Tham, Francesca Wei Inng Lim, Yunxin Chen, Shin Yeu Ong, Chandramouli Nagarajan, Jing Jing Lee, Yeow Tee Goh, Yeh Ching Linn, Yuh Shan Lee and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Blood cell therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Lawrence Cheng Kiat NgDepartment of Haematology, Singapore General Hospital, Singapore.
Christopher Shwei Wen ThamDepartment of Haematology, Singapore General Hospital, Singapore.
Francesca Wei Inng LimDepartment of Haematology, Singapore General Hospital, Singapore.
Yunxin ChenDepartment of Haematology, Singapore General Hospital, Singapore.
Shin Yeu OngDepartment of Haematology, Singapore General Hospital, Singapore.
Chandramouli NagarajanDepartment of Haematology, Singapore General Hospital, Singapore.
Jing Jing LeeDepartment of Haematology, Singapore General Hospital, Singapore.
Yeow Tee GohDepartment of Haematology, Singapore General Hospital, Singapore.
Yeh Ching LinnDepartment of Haematology, Singapore General Hospital, Singapore.
Yuh Shan LeeDepartment of Haematology, Singapore General Hospital, Singapore.
Colin Diong PhippsDepartment of Haematology, Singapore General Hospital, Singapore.
Jeffrey Kim Siang QuekDepartment of Haematology, Singapore General Hospital, Singapore.
Than HeinDepartment of Haematology, Singapore General Hospital, Singapore.
Jordan Chung Cheng HwangDepartment of Haematology, Singapore General Hospital, Singapore.
Nicholas GrigoropoulosDepartment of Haematology, Singapore General Hospital, Singapore.
William Ying Khee HwangDepartment of Haematology, Singapore General Hospital, Singapore.
Aloysius Yew Leng HoDepartment of Haematology, Singapore General Hospital, Singapore.
Singapore General Hospital · SGNational Cancer Centre Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aggressive T and NK/T-cell lymphoma are known to have a high risk of relapse and poor long-term prognosis. Hematopoietic stem cell transplantation has been performed as part of consolidation or salvage treatment. We retrospectively studied the outcomes of autologous (A) and allogeneic (allo) hematopoietic stem cell transplantation (SCT) in aggressive T and NK/T-cell lymphoma at our center between 2010 to 2020. Patients with nodal peripheral T-cell lymphoma (PTCL) that were younger than 65 years old who did not receive upfront autologous SCT (ASCT) at first complete remission were selected from our registry data for further comparison. Thirty-six patients underwent ASCT, and 16 patients underwent alloSCT. In the ASCT cohort, 18 patients with nodal PTCL who underwent upfront ASCT at first complete remission (upfront ASCT) were compared with 15 patients with nodal PTCL who were in first complete remission after single-line induction but did not receive ASCT. The two-year progression-free survival (PFS) and overall survival (OS) rates for the ASCT cohort were 58% and 73%, respectively. The two-year PFS and OS for the alloSCT cohort were 47% (

Indexed as

peripheral T-cell lymphomaT and NK/T cell lymphomatransplantation

Identifiers

PMID36714065
PMCPMC9847283
OpenAlexW4206386500

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.