Evidence map›Paper›PMID 36713916›Full record

ArticleFrontiers in psychiatry2022

Inflammation mediated the effect of dietary fiber on depressive symptoms.

Ting Zhang, Xiao-Mei Cui, Yu-Ying Zhang, Tao Xie, Yuan-Jia Deng, Fang-Xi Guo, Qi Wang, Qing-Feng Wu, Ming-Hua Dong, Xiao-Ting Luo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ting ZhangKey Laboratory of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou, China.
Xiao-Mei CuiSchool of Public Health and Health Management, Gannan Medical University, Ganzhou, China.
Yu-Ying ZhangSchool of Public Health and Health Management, Gannan Medical University, Ganzhou, China.
Tao XieSchool of Public Health and Health Management, Gannan Medical University, Ganzhou, China.
Yuan-Jia DengSchool of Public Health and Health Management, Gannan Medical University, Ganzhou, China.
Fang-Xi GuoSchool of Public Health and Health Management, Gannan Medical University, Ganzhou, China.
Qi WangDepartment of Epidemiology, Gannan Medical University, Ganzhou, China.
Qing-Feng WuDepartment of Epidemiology, Gannan Medical University, Ganzhou, China.
Ming-Hua DongDepartment of Epidemiology, Gannan Medical University, Ganzhou, China.
Xiao-Ting LuoKey Laboratory of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou, China.
Gannan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Previous studies showed that inflammation affects depressive symptoms. Dietary fiber may be associated with inflammation and depressive symptoms. We aimed to investigate the relationship between inflammation and depressive symptoms at different levels of dietary fiber intake and to explore whether dietary fiber affects depression through inflammation. Methods: A total of 8,430 National Health and Nutrition Examination Survey (NHANES) samples were collected between 2015 and 2018. Factor analysis was used to determine dietary patterns. Linear regression and logistic regression analysis were used to explore the relationship between nutrients, inflammation, and depressive symptoms, and the mediation analysis was conducted using the bootstrap method. Results: Factor 3 (dietary fiber and vitamins) was inversely associated with depressive symptoms and inflammation. The upper quartile scores of the dietary inflammatory index (DII) and C-reactive protein (CRP) were associated with depressive symptoms compared with controls (DII: Conclusion: In this study, we found that DII scores and CRP were not associated with depressive symptoms in participants with high dietary fiber intake, and inflammation partially mediates the effect of dietary fiber on depressive symptoms.

Indexed as

CRPdepressiondietary fiberdietary inflammatory indexnutrition

Identifiers

PMID36713916
PMCPMC9874690
OpenAlexW4315498603

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.