Evidence map›Paper›PMID 36713903›Full record

ArticleFrontiers in psychiatry2022

Non-antipsychotic medicines and modified electroconvulsive therapy are risk factors for hospital-acquired pneumonia in schizophrenia patients.

Yan Yang, Di Kong, Qiwen Li, Wei Chen, Guocheng Zhao, Xi Tan, Xincheng Huang, Zipeng Zhang, Can Feng, Min Xu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yan YangThe Fourth People's Hospital of Chengdu, Chengdu, Sichuan, China.
Di KongThe Fourth People's Hospital of Chengdu, Chengdu, Sichuan, China.
Qiwen LiThe Fourth People's Hospital of Chengdu, Chengdu, Sichuan, China.
Wei ChenThe Fourth People's Hospital of Chengdu, Chengdu, Sichuan, China.
Guocheng ZhaoThe Fourth People's Hospital of Chengdu, Chengdu, Sichuan, China.
Xi TanThe Fourth People's Hospital of Chengdu, Chengdu, Sichuan, China.
Xincheng HuangThe Fourth People's Hospital of Chengdu, Chengdu, Sichuan, China.
Zipeng ZhangThe Fourth People's Hospital of Chengdu, Chengdu, Sichuan, China.
Can FengThe Fourth People's Hospital of Chengdu, Chengdu, Sichuan, China.
Min XuThe Fourth People's Hospital of Chengdu, Chengdu, Sichuan, China.
Ying WanThe Fourth People's Hospital of Chengdu, Chengdu, Sichuan, China.
Mi YangThe Fourth People's Hospital of Chengdu, Chengdu, Sichuan, China.
The Fourth People's Hospital · CNFourth People's Hospital of Sichuan Province · CNUniversity of Electronic Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hospital-acquired pneumonia (HAP) has a significant and detrimental impact on schizophrenia patients. Non-antipsychotic medicines and modified electroconvulsive therapy (MECT) are frequently used in conjunction with antipsychotics to treat schizophrenia. Whether non-antipsychotic medicines or MECT are risk factors for HAP in schizophrenia treated with antipsychotics is still unknown. Methods: Patients with schizophrenia who were admitted to the Fourth People's Hospital of Chengdu between January 2015 and April 2022 were included in this retrospective cohort study. Individuals with HAP were 1:1 matched to individuals without HAP (non-HAP) using propensity score matching (PSM). The risk factors for HAP were analyzed by comparing the two groups. Results: A total of 7,085 schizophrenia patients were included in this study, with a mean age of 39.77 ± 14.45 years. 193 patients developed HAP on an average of 22.26 ± 21.68 days after admission with an incidence of 2.73%. After 1:1 PSM, 192 patients from each group (HAP and non-HAP) were included. The HAP group had significantly more patients with MECT and taking benzodiazepines, antidepressants, mood stabilizers, and anti-parkinsonians both before and after PSM by Conclusion: The incidence of HAP in schizophrenia patients in our cohort was 2.73%. MECT and non-antipsychotic medicines, including benzodiazepines and mood stabilizers were risk factors for HAP in schizophrenia patients treated with antipsychotics.

Indexed as

benzodiazepineshospital-acquired pneumoniamodified electroconvulsive therapymood stabilizersschizophrenia

Identifiers

PMID36713903
PMCPMC9880231
OpenAlexW4316041205

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.