Evidence map›Paper›PMID 36713402›Full record

ArticleFrontiers in immunology2022

A novel TBK1/IKKϵ is involved in immune response and interacts with MyD88 and MAVS in the scallop

Wenjuan Liu, Jilv Ma, Jiwen Chen, Baoyu Huang, Fengchen Liu, Lingling Li, Nini Fan, Fangshu Li, Yanxin Zheng, Xuekai Zhang and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Wenjuan LiuSchool of Agriculture, Ludong University, Yantai, China.
Jilv MaSchool of Agriculture, Ludong University, Yantai, China.
Jiwen ChenSchool of Agriculture, Ludong University, Yantai, China.
Baoyu HuangSchool of Agriculture, Ludong University, Yantai, China.
Fengchen LiuSchool of Agriculture, Ludong University, Yantai, China.
Lingling LiSchool of Agriculture, Ludong University, Yantai, China.
Nini FanChangdao Enhancement and Experiment Station, Chinese Academy of Fishery Sciences, Yantai, China.
Fangshu LiSchool of Agriculture, Ludong University, Yantai, China.
Yanxin ZhengChangdao Enhancement and Experiment Station, Chinese Academy of Fishery Sciences, Yantai, China.
Xuekai ZhangSchool of Agriculture, Ludong University, Yantai, China.
Xiaona WangSchool of Agriculture, Ludong University, Yantai, China.
Xiaomei WangChangdao Enhancement and Experiment Station, Chinese Academy of Fishery Sciences, Yantai, China.
Lei WeiSchool of Agriculture, Ludong University, Yantai, China.
Yaqiong LiuSchool of Agriculture, Ludong University, Yantai, China.
Meiwei ZhangSchool of Agriculture, Ludong University, Yantai, China.
Yijing HanSchool of Agriculture, Ludong University, Yantai, China.
Xiaotong WangSchool of Agriculture, Ludong University, Yantai, China.
Ludong University · CNChinese Academy of Fishery Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhibitor of κB kinase (IKK) family proteins are key signaling molecules in the animal innate immune system and are considered master regulators of inflammation and innate immunity that act by controlling the activation of transcription factors such as NF-κB. However, few functional studies on IKK in invertebrates have been conducted, especially in marine mollusks. In this study, we cloned the IKK gene in the Zhikong scallop

Indexed as

I-kappa B KinasePectinidaeAdaptor Proteins, Signal TransducingAmino Acid SequenceAnimalsHEK293 CellsHumansImmunity, InnateMyeloid Differentiation Factor 88NF-kappa BPhylogenyProtein Serine-Threonine KinasesAdaptor Proteins, Signal TransducingI-kappa B KinaseMyeloid Differentiation Factor 88NF-kappa BProtein Serine-Threonine KinasesTBK1 protein, humanChlamys farreriinnate immunityMAVSMyD88TBK1/IKKϵ

Identifiers

PMID36713402
PMCPMC9879056
OpenAlexW4315780811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.