Evidence map›Paper›PMID 36713394›Full record

ArticleFrontiers in immunology2022

Differential expression of nuclear hormone receptors by dendritic cell subsets in human vaginal mucosa and skin.

HyeMee Joo, Chao Gu, Matthew Wiest, Dorothee Duluc, Emyly Fernandez, Verah Nyarige, Johnny Yi, SangKon Oh

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

HyeMee JooDepartment of Immunology, Mayo Clinic, Scottsdale, AZ, United States.
Chao GuDepartment of Immunology, Mayo Clinic, Scottsdale, AZ, United States.
Matthew WiestDepartment of Immunology, Mayo Clinic, Scottsdale, AZ, United States.
Dorothee DulucImmunoconcept, Centre National de la Recherche Scientifique (CNRS) UMR 5164, Bordeaux University, Bordeaux, France.
Emyly FernandezDepartment of Immunology, Mayo Clinic, Scottsdale, AZ, United States.
Verah NyarigeDepartment of Health Sciences Research, Mayo Clinic, Scottsdale, AZ, United States.
Johnny YiDepartment of Medical and Surgery Gynecology, Mayo Clinic, Phoenix, AZ, United States.
SangKon OhDepartment of Immunology, Mayo Clinic, Scottsdale, AZ, United States.
Mayo Clinic in Arizona · USCentre National de la Recherche Scientifique · FRMayo Clinic Hospital · US

Funding

Targeting Dendritic Cell Subsets in Human Vagina to Elicit Local ImmunityRC1AI087379 · NIAID · BAYLOR RESEARCH INSTITUTE · PI OH, SANGKON · 2010 to 2010
$500k
NIAID NIH HHS RC1 AI087379
6 · The paper itself

Abstract

Nuclear hormone receptors (NHRs) expressed by dendritic cells (DCs), the major immune inducers and regulators, could play important roles in host immunity. Assessment of NHRs expressed by DCs in the vaginal mucosa (VM), in comparison with those expressed by DCs in other tissues, will thus help us understand the immunology of human vagina. This study identified 16 NHR transcripts that are differentially expressed among 8 different antigen-presenting cell (APC) subsets isolated from human VM, skin, and blood. The expression profiles of NHRs were largely tissue specific. VM APCs expressed increased levels of

Indexed as

Dendritic CellsEstrogen Receptor alphaFemaleHLA-DR AntigensHumansMucous MembraneVaginaEstrogen Receptor alphaHLA-DR Antigensantigen-presenting cellsblooddendritic cellestrogen receptornuclear hormone receptorprogesterone receptorskinvaginal mucosa

Identifiers

PMID36713394
PMCPMC9880315
OpenAlexW4315797394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.