ArticleJournal of clinical tuberculosis and other mycobacterial diseases2023
Tuberculosis infection among children under six in contact with smear positive cases: A study in a hyper endemic area of Iran.
Article in Journal of clinical tuberculosis and other mycobacterial diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- Pediatric Tuberculosis Outside a Specialized TB Center: Clinical Presentation, Diagnostic Pathways, and Factors Associated with Microbiological Confirmation in a Romanian Tertiary Hospital.Microorganisms · 2026Article
- BCG vaccination and household TB exposure in childhood tuberculosis: a community-based case-control study in rural Bangladesh.BMC infectious diseases · 2026Article
- Risk factors and treatment outcomes of drug-resistant tuberculosis among patients attending Ndola Teaching Hospital, Zambia: a retrospective case-control study.The Pan African medical journal · 2026Article
- Household Clustering of High-Risk Contacts in Smear-Positive TB Patient Families: Evidence for Hotspot Households and Risk Stratification in Rural Eastern Cape.International journal of environmental research and public health · 2025Article
- [Molecular Epidemiological Analysis of Tuberculosis Transmission in Households in Republic of Korea, 2016-2024].Jugan geon-gang gwa jilbyeong · 2025Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Annually, tens of millions of children are being exposed to tuberculosisinfection. Note that children are in higher risk of getting infection and sever types of the disease, detecting the factors associated with transmission of the tuberculosis infection and disease to the exposed children is necessary for disease prevention within the community. Methods: In this retrospective cohort study, 50 children under 6 who were in close contact with 25 smear-positive pulmonary tuberculosis cases in Sistan-Baloochistanprovine, Iran, were investigated. Demographic, behavioral and clinical characteristics of children and index cases were collected and tuberculosis infection and disease was assessed using the WHO guidelines. Results: Of 50 children exposed to the active cases, 12 (24 %) were infected to tuberculosis but none of them had active disease. We also found significant associations of the history of diabetes mellitus in the index cases (p = 0.043) and large family size (p = 0.026) with the increased risk of infection among the exposed children. Conclusion: Children under six which are in close contact with diabetic tuberculosis cases in large families are in higher risk of getting infection.
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