Evidence map›Paper›PMID 36713299›Full record

ArticleNature synthesis2022

Combined radical and ionic approach for the enantioselective synthesis of β-functionalized amines from alcohols.

Kai Lang, Yang Hu, Wan-Chen Cindy Lee, X Peter Zhang

Open access · greenAbstract read
In one paragraph

Article in Nature synthesis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  6. Catalytic Metalloradical System for Radical 1,6-C(spJournal of the American Chemical Society · 2025
    Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kai LangDepartment of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA, USA.ORCID 0000-0003-2778-8478
Yang HuDepartment of Chemistry, University of South Florida, Tampa, FL, USA.
Wan-Chen Cindy LeeDepartment of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA, USA.
X Peter ZhangDepartment of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA, USA.ORCID 0000-0001-7574-8409
Boston College · USUniversity of South Florida · US

Funding

Stereoselective Radical Processes for C-H Alkylation and AminationR01GM132471 · NIGMS · BOSTON COLLEGE · PI ZHANG, X. PETER · 2020 to 2023
$1.7M
NIGMS NIH HHS R01 GM132471
6 · The paper itself

Abstract

Chiral amines are among the most important organic compounds and have widespread applications. Enantioselective construction of chiral amines is a major aim in organic synthesis. Among synthetic methods, direct functionalization of omnipresent C-H bonds with common organic nitrogen compounds represents one of the most attractive strategies. However, C-H amination strategies are largely limited to constructing a specific type of

Identifiers

PMID36713299
PMCPMC9881596
OpenAlexW4285087437

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.