ArticleFrontiers in microbiology2022
A rapid method for detecting and distinguishing metallo-β-lactamase-and serine carbapenemase-producing
Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
- Bimetallic nanotubes enhanced MALDI-TOF MS for rapid detection of carbapenemase activity in Klebsiella pneumoniae.Analytical and bioanalytical chemistry · 2025Article
- Paradoxical carbapenemase activity detected by modified carbapenemase inactivation (mCIM) method inJournal of clinical microbiology · 2025Article
- Small-Molecule Probes: Recent Progress in the Rapid Detection of Carbapenemase-Producing Bacteria.Pharmaceutics · 2025Review
- Revisiting the Metallo-International journal of microbiology · 2025Review
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Authors and funding
9 authors at 2 institutions in 1 country.
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Abstract
Introduction: Carbapenemase-producing Methods: To assess the specificity and sensitivity of the method, 110 carbapenemase-producing and 72 carbapenemase-negative Results: Based on the presence, absence, and recovery of the IPM-cyano-4-hydroxy-cinnamic acid-specific waveform peak near 479 m/z, the detection sensitivity and specificity of the method were 98.2 and 100%, respectively. Discussion: Although CPE detection by MALDI-TOF MS has been studied previously, our method distinguishes between metallo-β-lactamase and serine carbapenemases, which will be very helpful for the clinical selection of antibiotics.
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