ArticleCytotechnology2023
The gill epithelial cell lines RTgill-W1, from Rainbow trout and ASG-10, from Atlantic salmon, exert different toxicity profiles towards rotenone.
Article in Cytotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Salt Treatment Confers Protection Against Acute Carp Edema Virus Reinfection While Promoting Viral Persistence.Journal of fish diseases · 2026Article
- In Vitro Toxicity Assessment of Tire-related Chemicals in Cells from Diverse Fish Species.Bulletin of environmental contamination and toxicology · 2026Article
- Improve your success with fish cell lines-small things that matter.In vitro cellular & developmental biology. Animal · 2026Review
- Atlantic Salmon (Toxics · 2025Article
- Isolation and characterisation of two epithelial-like cell lines from the gills of Chrysophrys auratus (Australasian snapper) and Oncorhynchus tshawytscha (Chinook salmon) and their use in aquatic toxicology.In vitro cellular & developmental biology. Animal · 2025Article
- The impact of beauvericin on rainbow trout intestinal epithelial cells at different temperatures and dosing methods.In vitro cellular & developmental biology. Animal · 2025Article
- Hazard identification and characterization of leachable chemicals from plastic products - a new PARC project.Frontiers in toxicology · 2025Article
- Complex II ambiguities-FADHThe Journal of biological chemistry · 2024Review
- Functional and molecular characterization of the Atlantic salmon gill epithelium cell line ASG-10; a tool forFrontiers in molecular biosciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to ensure the proper use and interpretation of results from laboratory test systems, it is important to know the characteristics of your test system. Here we compare mitochondria and the handling of reactive oxygen species (ROS) in two gill epithelial cell lines, the well-known RTgill-W1 cell line from Rainbow trout and the newly established ASG-10 cell line from Atlantic salmon. Rotenone was used to trigger ROS production. Rotenone reduced metabolic activity and induced cell death in both cell lines, with RTgill-W1 far more sensitive than ASG-10. In untreated cells, the mitochondria appear to be more fragmented in RTgill-W1 cells compared to ASG-10 cells. Furthermore, rotenone induced mitochondrial fragmentation, reduced mitochondria membrane potential (Δψm) and increased ROS generation in both cell lines. Glutathione (GSH) and catalase is important to maintain the cellular oxidative balance by eliminating hydrogen peroxide (H Graphical abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s10616-022-00560-0.
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Registered trials
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