Evidence map›Paper›PMID 36713047›Full record

ArticleJournal of inflammation research2023

Systemic Inflammation Markers Associated with Bone Mineral Density in perimenopausal and Postmenopausal Women.

Yijie Chen, Jingjing Yu, Lan Shi, Shuyang Han, Jun Chen, Zhumei Sheng, Miao Deng, Xuejing Jin, Zhifen Zhang

Open access · goldAbstract read
In one paragraph

Article in Journal of inflammation research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. The systemic inflammation response index is independently associated with incident fracture risk in older women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yijie Chen *The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, People's Republic of China.ORCID 0000-0001-5856-6451
Jingjing Yu *School of Public Health, Hangzhou Normal University, Hangzhou, People's Republic of China.
Lan ShiThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, People's Republic of China.
Shuyang HanThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, People's Republic of China.
Jun ChenThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, People's Republic of China.
Zhumei ShengDepartment of the Reproductive Endocrinology Division, Hangzhou Women's Hospital (Hangzhou Maternity and Child Health Care Hospital), Hangzhou, People's Republic of China.
Miao DengDepartment of the Reproductive Endocrinology Division, Hangzhou Women's Hospital (Hangzhou Maternity and Child Health Care Hospital), Hangzhou, People's Republic of China.
Xuejing JinThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, People's Republic of China.
Zhifen ZhangThe Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, People's Republic of China.
Zhejiang Chinese Medical University · CNHangzhou Women’s Hospital · CNHangzhou Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this research was to determine whether systemic inflammatory indicators, including aggregate index of systemic inflammation (AISI), neutrophils lymphocyte to platelet ratio (NLPR), systemic immune-inflammation index (SII), and systemic inflammation response index (SIRI), are related to bone mineral density (BMD) in perimenopausal and postmenopausal women. Methods: One hundred and eighty-one perimenopausal and 390 postmenopausal women were enrolled in this cross-sectional study. Continuous variables by analysis of variance and Kruskal Wallis test for comparing the clinical characteristics. Linear regression analysis was conducted to investigate the associations between inflammatory indicators with BMD. The comparison between the subgroups was performed using the nonparametric test and the Results: AISI, NLPR, SII, and SIRI quartile values were inversely associated with BMD in menopausal women ( Conclusion: The quartile values of AISI, SII, and SIRI were inversely associated with BMD in postmenopausal women, following adjustment for individual variables, hormone profiles and glucolipid metabolism profiles. AISI, SII, and SIRI have potential to be important tools for screening and prevention of bone loss in menopausal women in future clinical practice.

Indexed as

cross-sectional studiesfemalefemur neckinflammationmenopauseregression analysis

Identifiers

PMID36713047
PMCPMC9879040
OpenAlexW4318542900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.