Evidence map›Paper›PMID 36713040›Full record

ArticleHeart rhythm O22023

Invasive electrophysiological testing to predict and guide permanent pacemaker implantation after transcatheter aortic valve implantation: A meta-analysis.

Konstantinos C Siontis, Abdalla Kara Balla, Yong-Mei Cha, Thomas Pilgrim, Romy Sweda, Laurent Roten, Tobias Reichlin, Paul A Friedman, Stephan Windecker, George C M Siontis

Open access · goldAbstract read
In one paragraph

Article in Heart rhythm O2, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Conduction Disorders: The Achilles' Heel of TAVR?Journal of clinical medicine · 2026
    Review
  3. A Streamline Strategy for Indication and Length of Telemetry Monitoring After TAVR.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Observational
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Konstantinos C SiontisDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Abdalla Kara BallaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Yong-Mei ChaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Thomas PilgrimDepartment of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.
Romy SwedaDepartment of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.
Laurent RotenDepartment of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.
Tobias ReichlinDepartment of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.
Paul A FriedmanDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Stephan WindeckerDepartment of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.
George C M SiontisDepartment of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.
University of Bern · CHMayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atrioventricular conduction abnormalities after transcatheter aortic valve implantation (TAVI) are common. The value of electrophysiological study (EPS) for risk stratification of high-grade atrioventricular block (HG-AVB) and guidance of permanent pacemaker (PPM) implantation is poorly defined. Objective: The purpose of this study was to identify EPS parameters associated with HG-AVB and determine the value of EPS-guided PPM implantation after TAVI. Methods: We performed a systematic review and meta-analysis of studies investigating the value of EPS parameters for risk stratification of TAVI-related HG-AVB and for guidance of PPM implantation among patients with equivocal PPM indications after TAVI. Results: Eighteen studies (1230 patients) were eligible. In 7 studies, EPS was performed only after TAVI, whereas in 11 studies EPS was performed both before and after TAVI. Overall PPM implantation rate for HG-AVB was 16%. AV conduction intervals prolonged after TAVI, with the AH and HV intervals showing the largest magnitude of changes. Pre-TAVI HV >70 ms and the absolute value of the post-TAVI HV interval were associated with subsequent HG-AVB and PPM implantation with odds ratios of 2.53 (95% confidence interval [CI] 1.11-5.81; Conclusion: Selective EPS testing may assist in the risk stratification of post-TAVI HG-AVB and in the guidance of PPM implantation, especially in patients with equivocal PPM indications post-TAVI.

Indexed as

Aortic stenosisElectrophysiological studyPermanent pacemakerRisk stratificationTranscatheter aortic valve implantation

Identifiers

PMID36713040
PMCPMC9877393
OpenAlexW4307153757

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.