ArticleOxidative medicine and cellular longevity2023
Microbiota from Exercise Mice Counteracts High-Fat High-Cholesterol Diet-Induced Cognitive Impairment in C57BL/6 Mice.
Article in Oxidative medicine and cellular longevity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 23 citations in OpenAlex.
- Exercise-Mediated Molecular Mechanisms of Antidepressant Effects: The Role of the Microbiota-Gut-Brain Axis.International journal of molecular sciences · 2026Review
- The combined effects of probiotic and high-intensity interval training on memory function in high fat diet-fed rats.Behavioral and brain functions : BBF · 2026Article
- Leonurine alleviates DSS-induced colitis in mice by activating the PINK1/Parkin-mediated mitophagy pathway: an integrated network pharmacology and experimental validation study.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Defining the Intestinal eCBome and Oxylipin Signaling Systems in a TDP-43 Mouse Model of Frontotemporal Dementia.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Organ-Specific Regulation of Systemic Aging: Focus on the Brain, Skeletal Muscle, and Gut.Cells · 2026Review
- Exercise prescription for mood and cognition: targeting the microbiota-gut-brain axis through short-chain fatty acids.Frontiers in microbiology · 2026Review
- Aerobic exercise alleviates cognitive impairment in T2DM mice through gut microbiota.Scientific reports · 2025Article
- Exercise-Induced Short-Chain Fatty Acids: A Novel Therapeutic Target in Type 2 Diabetes Mellitus with Sarcopenia.Aging and disease · 2025Review
- Exercise, Diet, and Brain Health: From the Perspective of Gut Microbiota Regulation.Nutrients · 2025Review
- A preliminary study on the changes of fecal short chain fatty acids in patients with traumatic spinal cord injury in the chronic phase.Spinal cord series and cases · 2025Observational
- The Cross-Talk Between the Peripheral and Brain Cholesterol Metabolisms.Current issues in molecular biology · 2025Review
- Exploring the Relationship Between Sporadic Creutzfeldt-Jakob Disease and Gut Microbiota Through a Mendelian Randomization Study.Molecular neurobiology · 2025Article
- Exercise mitigates Alzheimer's disease by targeting ferroptosis driven by cellular senescence.Frontiers in cell and developmental biology · 2025Review
- Exercise modulation of gut microbiota in Alzheimer's disease: pathophysiological mechanisms and therapeutic perspectives.Frontiers in aging neuroscience · 2025Review
- The Effects of Appropriate Perioperative Exercise on Perioperative Neurocognitive Disorders: a Narrative Review.Molecular neurobiology · 2024Review
- Review
- Atherosclerosis, gut microbiome, and exercise in a meta-omics perspective: a literature review.PeerJ · 2024Review
- Microbiota-gut-brain axis: the mediator of exercise and brain health.Psychoradiology · 2024Article
- Gut microbiota: a novel target for exercise-mediated regulation of NLRP3 inflammasome activation.Frontiers in microbiology · 2024Review
- The role of gut microorganisms and metabolites in intracerebral hemorrhagic stroke: a comprehensive review.Frontiers in neuroscience · 2024Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gut microbes may be the critical mediators for the cognitive enhancing effects of exercise. Via fecal microbiota transplantation (FMT), this study is aimed at determining the mechanism of how voluntary exercise improved learning and memory ability impairment post a high-fat, high-cholesterol (HFHC) diet. The learning and memory abilities assessed via the Morris water maze in the FMT recipient group of voluntary exercising mice were improved compared to sedentary group. 16S rRNA gene sequencing results indicated that exercise-induced changes in gut microbiota distribution were transmissible, mainly in terms of elevated
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.