Evidence map›Paper›PMID 36713011›Full record

ArticleEuropean heart journal. Digital health2022

A clinician's guide to understanding and critically appraising machine learning studies: a checklist for Ruling Out Bias Using Standard Tools in Machine Learning (ROBUST-ML).

Salah S Al-Zaiti, Alaa A Alghwiri, Xiao Hu, Gilles Clermont, Aaron Peace, Peter Macfarlane, Raymond Bond

Abstract read
In one paragraph

Article in European heart journal. Digital health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  2. Pooled it
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  10. In defense of empathic informatics.Journal of the American Medical Informatics Association : JAMIA · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Salah S Al-ZaitiDepartment of Acute and Tertiary Care, Department of Emergency Medicine, and Division of Cardiology, University of Pittsburgh, Pittsburgh PA, USA.ORCID https://orcid.org/0000-0002-6862-0658
Alaa A AlghwiriData Science Core, The Provost Office, University of Pittsburgh, Pittsburgh PA, USA.
Xiao HuCenter for Data Science, Emory University, Atlanta, GA, USA.
Gilles ClermontDepartments of Critical Care Medicine, Mathematics, Clinical and Translational Science, and Industrial Engineering, University of Pittsburgh, Pittsburgh, PA, USA.
Aaron PeaceThe Clinical Translational Research and Innovation Centre, Northern Ireland, UK.ORCID https://orcid.org/0000-0001-9556-7509
Peter MacfarlaneInstitute of Health and Wellbeing, Electrocardiology Section, University of Glasgow, Glasgow, UK.
Raymond BondSchool of Computing, Ulster University, Ulster, UK.ORCID https://orcid.org/0000-0002-1078-2232

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing functional machine learning (ML)-based models to address unmet clinical needs requires unique considerations for optimal clinical utility. Recent debates about the rigours, transparency, explainability, and reproducibility of ML models, terms which are defined in this article, have raised concerns about their clinical utility and suitability for integration in current evidence-based practice paradigms. This featured article focuses on increasing the literacy of ML among clinicians by providing them with the knowledge and tools needed to understand and critically appraise clinical studies focused on ML. A checklist is provided for evaluating the rigour and reproducibility of the four ML building blocks: data curation, feature engineering, model development, and clinical deployment. Checklists like this are important for quality assurance and to ensure that ML studies are rigourously and confidently reviewed by clinicians and are guided by domain knowledge of the setting in which the findings will be applied. Bridging the gap between clinicians, healthcare scientists, and ML engineers can address many shortcomings and pitfalls of ML-based solutions and their potential deployment at the bedside.

Indexed as

BiasCritical appraisalGuidelinesHealthcareMachine learningQuality

Identifiers

PMID36713011
PMCPMC9708024

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.