Evidence map›Paper›PMID 36713004›Full record

ArticleEuropean heart journal. Digital health2022

Short-term prediction of atrial fibrillation from ambulatory monitoring ECG using a deep neural network.

Jagmeet P Singh, Julien Fontanarava, Grégoire de Massé, Tanner Carbonati, Jia Li, Christine Henry, Laurent Fiorina

Open access · goldAbstract read
In one paragraph

Article in European heart journal. Digital health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Review
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  7. Review
  8. Article
  9. Article
  10. Adopting artificial intelligence in cardiovascular medicine: a scoping review.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  11. Article
  12. Can 24 h of ambulatory ECG be used to triage patients to extended monitoring?Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Jagmeet P SinghMassachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.ORCID https://orcid.org/0000-0002-2724-529X
Julien FontanaravaCardiologs, 136 rue Saint Denis, 75002 Paris, France.
Grégoire de MasséCardiologs, 136 rue Saint Denis, 75002 Paris, France.
Tanner CarbonatiCardiologs, 136 rue Saint Denis, 75002 Paris, France.
Jia LiCardiologs, 136 rue Saint Denis, 75002 Paris, France.
Christine HenryCardiologs, 136 rue Saint Denis, 75002 Paris, France.
Laurent FiorinaRamsay Santé, Institut Cardiovasculaire Paris Sud, Hôpital privé Jacques Cartier, 91300 Massy, France.
Institut Cardiovasculaire Paris Sud · FRMassachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Atrial fibrillation (AF) is associated with significant morbidity but remains underdiagnosed. A 24 h ambulatory electrocardiogram (ECG) is largely used as a tool to document AF but yield remains limited. We hypothesize that a deep learning model can identify patients at risk of AF in the 2 weeks following a 24 h ambulatory ECG with no documented AF. Methods and results: We identified a training set of Holter recordings of 7-15 days duration, in which no AF could be found in the first 24 h. We trained a neural network to predict the presence or absence of AF in the 15 following days, using only the first 24 h of the recording. We evaluated the neural network on a testing set and an external data set not used during algorithm development. In the testing data set, out of 9993 Holters with no AF on the first day, we found 361 (4%) recordings with AF within the 15 subsequent days of monitoring [5808, 218 (4%), respectively in the external data set]. The neural network could discriminate future AF with an area under the receiver operating curve, a sensitivity, and specificity of 79.4%, 76%, and 69%, respectively (75.8%, 78%, and 58% in the external data set), and outperformed ECG features previously shown to be predictive of AF. Conclusion: We show here the very first study of short-term AF prediction using 24 h Holter monitoring. This could help identify patients who would benefit the most from longer recordings and proactively initiate treatment and AF mitigation strategies in high-risk patients.

Indexed as

Ambulatory monitoringAtrial fibrillationDeep learningHolterRisk prediction

Identifiers

PMID36713004
PMCPMC9708000
OpenAlexW4226325681

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.