Evidence map›Paper›PMID 36712939›Full record

ArticlePNAS nexus2023

Pharmacological potentiators of the calcium signaling cascade identified by high-throughput screening.

Michele Genovese, Daniela Guidone, Martina Buccirossi, Anna Borrelli, Alejandra Rodriguez-Gimeno, Fabio Bertozzi, Tiziano Bandiera, Luis J V Galietta

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PNAS nexus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Detailed Analysis of ITPR1 Missense Variants Guides Diagnostics and Therapeutic Design.Movement disorders : official journal of the Movement Disorder Society · 2024
    Article
  5. Cold Spring Harbor molecular case studies · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Michele GenoveseTelethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, 80078 Naples, Italy.ORCID https://orcid.org/0000-0002-9350-1191
Daniela GuidoneTelethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, 80078 Naples, Italy.
Martina BuccirossiTelethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, 80078 Naples, Italy.
Anna BorrelliTelethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, 80078 Naples, Italy.
Alejandra Rodriguez-GimenoD3 PharmaChemistry, Italian Institute of Technology (IIT), Via Morego, 3016163, Genoa, Italy.
Fabio BertozziD3 PharmaChemistry, Italian Institute of Technology (IIT), Via Morego, 3016163, Genoa, Italy.
Tiziano BandieraD3 PharmaChemistry, Italian Institute of Technology (IIT), Via Morego, 3016163, Genoa, Italy.
Luis J V GaliettaTelethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, 80078 Naples, Italy.ORCID https://orcid.org/0000-0001-8686-3461
Telethon Institute Of Genetics And Medicine · ITItalian Institute of Technology · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pharmacological modulators of the Ca

Indexed as

calcium signalinghigh throughput screeninginositol triphosphate receptorphospholipase Cpurinergic receptor

Identifiers

PMID36712939
PMCPMC9830948
OpenAlexW4312045313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.