Evidence map›Paper›PMID 36712918›Full record

ArticleRSC advances2023

Schwann cell-matrix coated PCL-MWCNT multifunctional nanofibrous scaffolds for neural regeneration.

Yas Al-Hadeethi, Aishwarya Nagarajan, Srividya Hanuman, Hiba Mohammed, Aakanksha M Vetekar, Goutam Thakur, Le N M Dinh, Yin Yao, E M Mkawi, Mahmoud Ali Hussein and 2 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 4 countries.

Yas Al-HadeethiDepartment of Physics, Faculty of Science, King Abdulaziz University Jeddah 21589 Saudi Arabia.
Aishwarya NagarajanManipal Institute of Regenerative Medicine, Manipal Academy of Higher Education Manipal 576104 Bengaluru Karnataka India manasa.nune@manipal.edu.
Srividya HanumanManipal Institute of Regenerative Medicine, Manipal Academy of Higher Education Manipal 576104 Bengaluru Karnataka India manasa.nune@manipal.edu.
Hiba MohammedFondazione Novara Sviluppo 28100 Novara Italy.
Aakanksha M VetekarManipal Institute of Regenerative Medicine, Manipal Academy of Higher Education Manipal 576104 Bengaluru Karnataka India manasa.nune@manipal.edu.
Goutam ThakurDepartment of Biomedical Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education Manipal 576104 Karnataka India.ORCID https://orcid.org/0000-0002-1449-9581
Le N M DinhCluster for Advanced Macromolecular Design (CAMD), School of Chemical Engineering, University of New South Wales Sydney NSW 2052 Australia agarwalvipul84@gmail.com.
Yin YaoCluster for Advanced Macromolecular Design (CAMD), School of Chemical Engineering, University of New South Wales Sydney NSW 2052 Australia agarwalvipul84@gmail.com.
E M MkawiDepartment of Physics, Faculty of Science, King Abdulaziz University Jeddah 21589 Saudi Arabia.
Mahmoud Ali HusseinDepartment of Chemistry, Faculty of Science, King Abdelaziz University Jeddah 21589 Saudi Arabia.ORCID https://orcid.org/0000-0002-5128-5136
Vipul AgarwalCluster for Advanced Macromolecular Design (CAMD), School of Chemical Engineering, University of New South Wales Sydney NSW 2052 Australia agarwalvipul84@gmail.com.ORCID https://orcid.org/0000-0002-6239-5410
Manasa NuneManipal Institute of Regenerative Medicine, Manipal Academy of Higher Education Manipal 576104 Bengaluru Karnataka India manasa.nune@manipal.edu.ORCID https://orcid.org/0000-0001-5328-5693
Manipal Academy of Higher Education · INKing Abdulaziz University · SAUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nerve tissue engineering aims to create scaffolds that promote nerve regeneration in the damaged peripheral nervous system. However, there remain some challenges in the construction of scaffolds in terms of mechanical properties and cellular behaviour. The present work aims to develop multifunctional implantable nanofibrous scaffolds for nerve regeneration. Using electrospinning, nanofibrous neat polycaprolactone (PCL) and PCL/multiwalled carbon nanotubes (PCL-MWCNT) composite scaffolds were prepared in random and aligned morphology. Schwann cells and their secreted biochemical factors are responsible for neuronal survival in the peripheral nervous system. Therefore, the acellular matrix of Schwann cells was spin-coated on the PCL-MWCNT scaffolds to aid nerve regeneration. Physicochemical and mechanical properties, and the

Identifiers

PMID36712918
PMCPMC9814035
OpenAlexW4313509082

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.