Evidence map›Paper›PMID 36712887›Full record

ArticleFrontiers in genetics2022

Governing biotechnology to provide safety and security and address ethical, legal, and social implications.

Benjamin Trump, Christopher Cummings, Kasia Klasa, Stephanie Galaitsi, Igor Linkov

Abstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
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  10. Advancements in genetic studies of mushrooms: a comprehensive review.World journal of microbiology & biotechnology · 2024
    Review
  11. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2024
    Article
  12. Article
  13. Article
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  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Benjamin TrumpEngineering Research and Development Center, United States Army Corps of Engineers, Vicksburg, MS, United States.
Christopher CummingsEngineering Research and Development Center, United States Army Corps of Engineers, Vicksburg, MS, United States.
Kasia KlasaDepartment of Healthcare Management and Policy, University of Michigan School of Public Health, Ann Arbor, MI, United States.
Stephanie GalaitsiEngineering Research and Development Center, United States Army Corps of Engineers, Vicksburg, MS, United States.
Igor LinkovEngineering Research and Development Center, United States Army Corps of Engineers, Vicksburg, MS, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of biotechnology has produced a wide variety of materials and products which are rapidly entering the commercial marketplace. While many developments promise revolutionary benefits, some of them pose uncertain or largely untested risks and may spur debate, consternation, and outrage from individuals and groups who may be affected by their development and use. In this paper we show that the success of any advanced genetic development and usage requires that the creators establish technical soundness, ensure safety and security, and transparently represent the product's ethical, legal, and social implications (ELSI). We further identify how failures to address ELSI can manifest as significant roadblocks to product acceptance and adoption and advocate for use of the "safety-by-design" governance philosophy. This approach requires addressing risk

Indexed as

biotechnologyELSIgovernancepolicysafety-by-designsynthetic biology

Identifiers

PMID36712887
PMCPMC9873990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.