Evidence map›Paper›PMID 36712777›Full record

ArticleCureus2022

A Comparative Morphometric and Histological Study of Human Fetus and Fetal Pancreas in Hyperglycemic and Normoglycemic Mothers.

Rashmi Malhotra, Bharti Jakhar, Kanchan Bisht, Ravi Kant, Ashok Singh, Kavita Khoiwal, Brijendra Singh

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rashmi MalhotraAnatomy, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Bharti JakharAnatomy, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Kanchan BishtAnatomy, All India Institute of Medical Sciences Rishikesh, Rishikesh, IND.
Ravi KantGeneral Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Ashok SinghPathology/Histopathology/Renal Pathology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Kavita KhoiwalObstetrics and Gynecology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Brijendra SinghAnatomy, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Seema Dental College and Hospital · INAll India Institute of Medical Sciences Rishikesh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA significant percentage of pregnancies with gestational diabetes mellitus (GDM) has been found to result in the delivery of macrosomic babies. The current study intends to highlight the correlation between maternal diabetes and fetal parameters as well as the histogenesis of the fetal pancreas in humans. MATERIALS AND

methodsThe study included thirty aborted fetuses, categorized into seven groups according to their gestational age. Morphometric analysis of fetal parameters and fetal pancreas was done, and the values were compared within different gestational age groups. Pancreatic tissue was processed, stained with Hematoxylin & Eosin, and examined. A comparison was then made between fetuses with and without gestational diabetes.  Results: All the fetal biometrics as well as pancreatic parameters showed greater numeric values in mothers with GDM as compared to the controls of the same gestational age groups. However, the difference was not statistically significant. Histogenesis in such fetuses revealed GDM-related hyperplasia of islets of Langerhans.

conclusionA timely diagnosis of GDM is thus of paramount significance due to its potential implications so that appropriate interventions can be done on time, to improve the overall outcome.

Indexed as

gestational agegestational diabetes mellitushistogenesismacrosomicparameters

Identifiers

PMID36712777
PMCPMC9879539
OpenAlexW4312207689

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.