Evidence map›Paper›PMID 36712716›Full record

ReviewCureus2022

The Spontaneous Regression of Primary Gastrointestinal Malignancies: An Observational Review.

Carlos D Minacapelli, Philip Leuszkiewicz, Ankoor Patel, Carolyn Catalano, George Abdelsayed, Alexander Lalos, Vinod Rustgi

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Rare Case of Spontaneous Regression in Primary Gastric Diffuse Large B Cell Lymphoma.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. What Can Trigger Spontaneous Regression of Breast Cancer?Diagnostics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Carlos D MinacapelliMedicine, Division of Gastroenterology and Hepatology, Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.
Philip LeuszkiewiczMedicine, Division of Gastroenterology and Hepatology, Rutgers Robert Wood Johnson Medical School, New Brusnwick, USA.
Ankoor PatelMedicine, Division of Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.
Carolyn CatalanoMedicine, Division of Gastroenterology and Hepatology, Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.
George AbdelsayedMedicine, Division of Gastroenterology and Hepatology, Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.
Alexander LalosMedicine, Division of Gastroenterology and Hepatology, Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.
Vinod RustgiMedicine, Division of Gastroenterology and Hepatology, Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.
Johnson University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spontaneous regression or remission (SR) of cancer, often described as the partial or complete disappearance of a malignant tumor in the absence of all medical treatment and therapy, is a well-documented phenomenon. With efforts ongoing to establish cancer treatments that limit undesirable outcomes and adverse effects, these uncommon occurrences of SR carry significant implications for novel therapies and warrant further investigation. While several case studies have reported instances of SR in gastrointestinal (GI) malignancies, a comprehensive review of previous manifestations of SR in the GI tract remains lacking. The inclusion criteria for the rare phenomenon are also in need of an appropriate update that takes recent scientific advancements and emerging new medical technologies into account. Our analysis of 390 cases of SR in the GI tract focuses primarily on neoplasms of the hepatobiliary system and proposes an updated version of the older inclusion criteria for spontaneous regression.

Indexed as

gastroenterologygastrointestinal cancershepatobiliary systemhepatocellular carcinomahepatologyneoplasmsoncologyspontaneous regressionspontaneous remission

Identifiers

PMID36712716
PMCPMC9879583
OpenAlexW4312215299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.