Evidence map›Paper›PMID 36712642›Full record

ArticleRSC advances2023

Novel targeted pH-responsive drug delivery systems based on PEGMA-modified bimetallic Prussian blue analogs for breast cancer chemotherapy.

Qiang Chen, Xiaoyu Huang, Geyi Zhang, Jiangnan Li, Yang Liu, Xu Yan

Abstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qiang ChenDepartment of Orthopedics, The First Affiliated Hospital of Zhengzhou University No. 1, Jianshe East Road Zhengzhou 450052 P. R. China yanxu27@163.com.
Xiaoyu HuangDepartment of Gastroenterology, The First Affiliated Hospital of Zhengzhou University No. 1, Jianshe East Road Zhengzhou 450052 P. R. China.ORCID https://orcid.org/0000-0002-1002-1759
Geyi ZhangDepartment of Orthopedics, Yellow River Sanmenxia Affiliated Hospital of Henan University of Science and Technology No. 2, Heping West Road Sanmenxia 472000 P. R. China.
Jiangnan LiDepartment of Orthopedics, The First Affiliated Hospital of Zhengzhou University No. 1, Jianshe East Road Zhengzhou 450052 P. R. China yanxu27@163.com.
Yang LiuDepartment of Orthopedics, The First Affiliated Hospital of Zhengzhou University No. 1, Jianshe East Road Zhengzhou 450052 P. R. China yanxu27@163.com.
Xu YanDepartment of Orthopedics, The First Affiliated Hospital of Zhengzhou University No. 1, Jianshe East Road Zhengzhou 450052 P. R. China yanxu27@163.com.ORCID https://orcid.org/0000-0002-7731-007X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of novel nanoparticle-based drug delivery systems (nano-DDSs) with high loading capacity, low toxicity, precise targeting, and excellent biocompatibility remains urgent and important for the treatment of breast cancer (BC). Herein, novel BC-targeted nano-DDSs based on bimetallic Prussian blue analogs (PBA-DDSs) for intracellular doxorubicin (DOX) delivery and pH-responsive release were developed. Two kinds of bimetallic PBA, namely CuFe (copper-iron) PBA and CoFe (cobalt-iron) PBA, were synthesized by a coprecipitation method, followed by modification with polyethyleneglycol methacrylate (PEGMA)

Identifiers

PMID36712642
PMCPMC9828049

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.