Evidence map›Paper›PMID 36712434›Full record

ArticleFrontiers in neurology2022

Resting state network mapping in individuals using deep learning.

Patrick H Luckett, John J Lee, Ki Yun Park, Ryan V Raut, Karin L Meeker, Evan M Gordon, Abraham Z Snyder, Beau M Ances, Eric C Leuthardt, Joshua S Shimony

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Aging and the Spectral Properties of Brain Hemodynamics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  6. Anchoring Functional Connectivity to Individual Sulcal Morphology Yields Insights in a Pediatric Study of Reasoning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Patrick H LuckettDivision of Neurotechnology, Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, United States.
John J LeeMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, United States.
Ki Yun ParkDivision of Neurotechnology, Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, United States.
Ryan V RautDepartment of Physiology and Biophysics, University of Washington, Seattle, WA, United States.
Karin L MeekerDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, United States.
Evan M GordonDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, United States.
Abraham Z SnyderMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, United States.
Beau M AncesDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, United States.
Eric C LeuthardtDivision of Neurotechnology, Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, United States.
Joshua S ShimonyMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, United States.
Washington University in St. Louis · USMallinckrodt (United States) · USNeurological Surgery · USAllen Institute · US

Funding

Smartphone-Based "Burst" Cognitive AssessmentsP01AG003991 · NIA · WASHINGTON UNIVERSITY · PI JOHN MORRIS · 1985 to 2026
$69.5M
The natural history of AB accumulation in preclinical ADP01AG026276 · NIA · WASHINGTON UNIVERSITY · PI MORRIS, JOHN · 2005 to 2025
$49.5M
Research Education ComponentP30AG066444 · NIA · WASHINGTON UNIVERSITY · PI Susan Lynn Stark · 2020 to 2026
$28.7M
WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JEFFREY D MILBRANDT · 2020 to 2026
$15.5M
Training and DisseminationP41EB018783 · NIBIB · WADSWORTH CENTER · PI Jonathan Rickel Wolpaw · 2014 to 2026
$15.4M
Augmented Neurosurgical Navigation Software Using Resting State MRIR01CA203861 · NCI · WASHINGTON UNIVERSITY · PI Eric CLAUDE Leuthardt, JOSHUA S SHIMONY · 2017 to 2026
$5.8M
Functional Imaging Reserve in NeuroHIV (FIRN)R01MH118031 · NIMH · WASHINGTON UNIVERSITY · PI ANCES, BEAU M · 2018 to 2023
$3.7M
FALLS: A MARKER OF PRECLINICAL ALZHEIMERS DISEASER01AG057680 · NIA · WASHINGTON UNIVERSITY · PI ANCES, BEAU M, STARK, SUSAN LYNN · 2018 to 2022
$3.4M
NEUROIMAGING AND NEUROBEHAVIORAL BASIS OF RISKY DECISION-MAKING IN ADOLESCENTSR01NR012907 · NINR · WASHINGTON UNIVERSITY · PI ANCES, BEAU M · 2011 to 2015
$1.9M
THE EFFECTS OF AGE AND HIGHLY ACTIVE ANTIRETROVIRAL THERAPY ON BRAIN FUNCTIONR01NR012657 · NINR · WASHINGTON UNIVERSITY · PI ANCES, BEAU M · 2010 to 2014
$1.9M
Dynamics and Causal Functions of Large-Scale Cortical and Subcortical NetworksU01NS108916 · NINDS · WADSWORTH CENTER · PI WOLPAW, JONATHAN RICKEL · 2018 to 2019
$1.4M
Calibrated BOLD fMRI of HIV Associated Neurocognitive Impairment (HNCI)K23MH081786 · NIMH · WASHINGTON UNIVERSITY · PI ANCES, BEAU M · 2007 to 2012
$820k
NCI NIH HHS R01 CA203861NIA NIH HHS P01 AG003991NIA NIH HHS P01 AG026276NIA NIH HHS P30 AG066444NIA NIH HHS R01 AG057680NIBIB NIH HHS P41 EB018783NICHD NIH HHS P50 HD103525NIMH NIH HHS K23 MH081786NIMH NIH HHS R01 MH118031NINDS NIH HHS U01 NS108916NINR NIH HHS R01 NR012657NINR NIH HHS R01 NR012907
6 · The paper itself

Abstract

Introduction: Resting state functional MRI (RS-fMRI) is currently used in numerous clinical and research settings. The localization of resting state networks (RSNs) has been utilized in applications ranging from group analysis of neurodegenerative diseases to individual network mapping for pre-surgical planning of tumor resections. Reproducibility of these results has been shown to require a substantial amount of high-quality data, which is not often available in clinical or research settings. Methods: In this work, we report voxelwise mapping of a standard set of RSNs using a novel deep 3D convolutional neural network (3DCNN). The 3DCNN was trained on publicly available functional MRI data acquired in Results: Our results indicate this method can be applied in individual subjects and is highly resistant to both noisy data and fewer RS-fMRI time points than are typically acquired. Further, our results show core regions within each network that exhibit high average probability and low STD. Discussion: The 3DCNN algorithm can generate individual RSN localization maps, which are necessary for clinical applications. The similarity between 3DCNN mapping results and task-based fMRI responses supports the association of specific functional tasks with RSNs.

Indexed as

brain mappingdeep learningmachine learningrepresentation of functionresting state functional MRI

Identifiers

PMID36712434
PMCPMC9878609
OpenAlexW4315781971

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.