Evidence map›Paper›PMID 36712039›Full record

ArticlebioRxiv : the preprint server for biology2023

Blind Assessment of Monomeric AlphaFold2 Protein Structure Models with Experimental NMR Data.

Ethan H Li, Laura Spaman, Roberto Tejero, Yuanpeng Janet Huang, Theresa A Ramelot, Keith J Fraga, James H Prestegard, Michael A Kennedy, Gaetano T Montelione

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Ethan H LiDepartment of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180 USA.ORCID 0000-0003-0754-4054
Laura SpamanDepartment of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180 USA.ORCID 0000-0003-3451-9620
Roberto TejeroDepartment of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180 USA.ORCID 0000-0003-2504-5988
Yuanpeng Janet HuangDepartment of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180 USA.ORCID 0000-0002-3374-786X
Theresa A RamelotDepartment of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180 USA.ORCID 0000-0002-0335-1573
Keith J FragaDepartment of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180 USA.ORCID 0000-0002-8930-6510
James H PrestegardComplex Carbohydrate Research Center, University of Georgia, Athens, GA 30602 USA.ORCID 0000-0002-1602-4790
Michael A KennedyDepartment of Chemistry and Biochemistry, Miami University, Oxford, OH 45056 USA.ORCID 0000-0001-6462-665X
Gaetano T MontelioneDepartment of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180 USA.ORCID 0000-0002-9440-3059

Funding

Hybrid Methods for Dynamic Structure Analysis of Proteins from Pathogenic MicroorganismsR35GM141818 · NIGMS · RENSSELAER POLYTECHNIC INSTITUTE · PI MONTELIONE, GAETANO T · 2021 to 2025
$3.3M
NIGMS NIH HHS R35 GM141818
6 · The paper itself

Abstract

Recent advances in molecular modeling of protein structures are changing the field of structural biology. Highlights: AF2 models assessed against NMR data for 9 monomeric proteins not used in training.AF2 models fit NMR data almost as well as the experimentally-determined structures.

Identifiers

PMID36712039
PMCPMC9882346

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.