Evidence map›Paper›PMID 36712030›Full record

ArticlebioRxiv : the preprint server for biology2023

Immune sensing of food allergens promotes aversive behaviour.

Esther B Florsheim, Nathaniel D Bachtel, Jaime Cullen, Bruna G C Lima, Mahdieh Godazgar, Cuiling Zhang, Fernando Carvalho, Gregory Gautier, Pierre Launay, Andrew Wang and 2 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 4 countries.

Esther B FlorsheimDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Nathaniel D BachtelDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Jaime CullenDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Bruna G C LimaDepartment of Pharmacology, University of São Paulo, São Paulo, SP 05508-000 SP, Brazil.
Mahdieh GodazgarDepartment of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06510, USA.
Cuiling ZhangDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Fernando CarvalhoDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Gregory GautierINSERM UMRS 1149; CNRS ERL 8252; University Paris Diderot, Sorbonne Paris Cite, Laboratoire d'excellence INFLAMEX, Paris 75018, France.
Pierre LaunayINSERM UMRS 1149; CNRS ERL 8252; University Paris Diderot, Sorbonne Paris Cite, Laboratoire d'excellence INFLAMEX, Paris 75018, France.
Andrew WangDepartment of Internal Medicine and Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.
Marcelo O DietrichDepartment of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06510, USA.
Ruslan MedzhitovDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Yale University · USCentre National de la Recherche Scientifique · FRHoward Hughes Medical Institute · USUniversidade de São Paulo · BR

Funding

Role of GDF15 in the Regulation of Host Tolerance to InflammationR01AI144152 · NIAID · YALE UNIVERSITY · PI MEDZHITOV, RUSLAN · 2019 to 2023
$2.1M
Mast cell regulation of food allergen induced malaise through GDF15-GFRAL signalingF30AI174787 · NIAID · YALE UNIVERSITY · PI BACHTEL, NATHANIEL DALE · 2023 to 2025
$121k
NIAID NIH HHS F30 AI174787NIAID NIH HHS R01 AI144152
6 · The paper itself

Abstract

In addition to its canonical function in protecting from pathogens, the immune system can also promote behavioural alterations

Identifiers

PMID36712030
PMCPMC9882358
OpenAlexW4317655870

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.