Evidence map›Paper›PMID 36711993›Full record

ArticlebioRxiv : the preprint server for biology2023

Artificial nanovesicles for dsRNA delivery in spray induced gene silencing for crop protection.

Lulu Qiao, Jonatan Niño-Sánchez, Rachael Hamby, Luca Capriotti, Angela Chen, Bruno Mezzetti, Hailing Jin

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 18 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 4 countries.

Lulu QiaoDepartment of Microbiology & Plant Pathology, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of California, Riverside, California 92521, USA.
Jonatan Niño-SánchezDepartment of Microbiology & Plant Pathology, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of California, Riverside, California 92521, USA.
Rachael HambyDepartment of Microbiology & Plant Pathology, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of California, Riverside, California 92521, USA.
Luca CapriottiDepartment of Agricultural, Food and Environmental Sciences, Marche Polytechnic University, 60131 Ancona, Italy.
Angela ChenDepartment of Microbiology & Plant Pathology, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of California, Riverside, California 92521, USA.
Bruno MezzettiDepartment of Agricultural, Food and Environmental Sciences, Marche Polytechnic University, 60131 Ancona, Italy.
Hailing JinDepartment of Microbiology & Plant Pathology, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of California, Riverside, California 92521, USA.
University of California, Riverside · USMarche Polytechnic University · IT

Funding

Cross-kingdom RNA communications between plant and fungal pathogensR35GM136379 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI JIN, HAILING · 2020 to 2024
$2.1M
NIGMS NIH HHS R35 GM136379
6 · The paper itself

Abstract

Spray-Induced Gene Silencing (SIGS) is an innovative and eco-friendly technology where topical application of pathogen gene-targeting RNAs to plant material can enable disease control. SIGS applications remain limited because of the instability of dsRNA, which can be rapidly degraded when exposed to various environmental conditions. Inspired by the natural mechanism of cross-kingdom RNAi through extracellular vesicle trafficking, we describe herein the use of artificial nanovesicles (AVs) for dsRNA encapsulation and control against the fungal pathogen,

Indexed as

double-stranded RNA (dsRNA)liposomesnanoparticlesRNA interferencesmall RNA (sRNA)spray-induced gene silencing (SIGS)uptake efficiency

Identifiers

PMID36711993
PMCPMC9882009
OpenAlexW4313650407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.